Pharmacological Activity of Compounds Extracted from Persimmon Peel (Diospyros kaki THUNB.)

被引:40
作者
Fukai, Satomi [1 ]
Tanimoto, Shinichi [1 ]
Maeda, Aki [1 ]
Fukuda, Hitomi [1 ]
Okada, Yoshiharu [1 ]
Nomura, Masato [1 ]
机构
[1] Kinki Univ, Grad Sch Syst Engn, Program Syst Engn, Hiroshima 7392116, Japan
关键词
Disopyros kaki THUNB; antioxidative activity; tyrosinase inhibiting activity; DAMAGE;
D O I
10.5650/jos.58.213
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Persimmon peels (Diospyros kaki THUNB.) are discarded during the production of dried fruit. The 2-methoxy-4-vinyl phenol (8) which is component of persimmon peel had high antioxidant activity on the DPPR (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay and SOD (superoxide dismutase) assay. And (8) had higher tyrosinase inhibiting activity than that of arbutin using both L-tyrosine and L-DOPA as substrates. In addition, tyrosinase inhibiting activity of synthesized 2-methoxy-4-vinylphenol glycoside (8a) was studied. (8a) had tyrosinase inhibiting activity, suggesting that (8a) has possibilities for ingredient of cosmetics that are possessed of whitening effect.
引用
收藏
页码:213 / 219
页数:7
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