Synthesis and characterization of novel N-para-ferrocenyl benzoyl dipeptide esters

被引：22

作者：

Savage, David

Alley, Steven R.

Goel, Alok

Hogan, Tara

Ida, Yoshiteru

Kelly, Paula N.

Lehmann, Laurent

Kenny, Peter T. M. ^{[1
]}

机构：

[1] Dublin City Univ, Sch Chem Sci, Dublin 9, Ireland

[2] Dublin City Univ, Natl Inst Cellular Biotechnol, Dublin 9, Ireland

[3] Showa Univ, Sch Pharmaceut Sci, Shinagawa Ku, Tokyo 1428555, Japan

来源：

INORGANIC CHEMISTRY COMMUNICATIONS | 2006年 / 9卷 / 12期

关键词：

ferrocene; bioorganometallic chemistry; tandem mass spectrometry; dipeptides; CV; ELECTROCHEMICAL ANION RECOGNITION; RAY CRYSTAL-STRUCTURES; AMINO-ACID ESTERS; STRUCTURAL-CHARACTERIZATION; METHYL-ESTER; REDOX; DERIVATIVES; CHAINS; PEPTIDES; FC;

D O I：

10.1016/j.inoche.2006.06.013

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

N-para-ferrocenyl benzoyl dipeptide esters 2-5 were prepared by coupling para-ferrocenyl benzoic acid I to the dipeptide ethyl esters GlyGly(OEt) 2, GlyAla(OEt) 3, GlyLeu(OEt) 4 and GlyPhe(OEt) 5. The compounds were fully characterized by a range of NMR spectroscopic techniques.. mass spectrometry (ESI-MS, FABMS, MS/MS) and cyclic voltammetry (CV). The a(1) and b(1) ions appeared at one mass unit less than the expected mass in the tandem mass spectra. The CV curves of compounds 2-5 exhibited quasi-reversible redox behavior similar to the Fc/Fc(+) redox couple and displayed oxidation potential values in the 50-55 mV range, against the Fc/Fc+ redox couple. (C) 2006 Elsevier B.V. All rights reserved.

引用

页码：1267 / 1270

页数：4

共 39 条

[1] FAST ATOM BOMBARDMENT OF SOLIDS (FAB) - A NEW ION-SOURCE FOR MASS-SPECTROMETRY [J].