Synthesis and biological evaluation of fatty hydrazides of by-products of oil processing industry

被引：15

作者：

Toliwal, S. ^{[1
]}

Jadav, K. ^{[1
]}

Patel, K. ^{[1
]}

机构：

[1] Inst Sci & Technol Adv Studies & Res ISTAR, Dept Ind Chem, Vallabh Vidyanagar 388120, Gujarat, India

来源：

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2009年 / 71卷 / 02期

关键词：

Acid oil; oil recovered from spent bleaching earth (ORSBE); oxadiazoles; triazoles; hydrazides; antibacterial; antifungal; streptomycin; immidil; TRIAZOLES;

D O I：

10.4103/0250-474X.54282

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Some new 2-alkyl-5-mercapto-1,3,4-Oxadiazoles and 3-alkyl-5-mercapto-1,2,3-4H triazoles were synthesized from hydrazides of acid oil and oil recovered from spent bleaching earth. These newly synthesized compounds were characterized on the basis of elemental analysis and evaluated for biological properties. Certain derivatives exhibited fairly high antibacterial and antifungal activities when compared with streptomycin and immidil used as standard antibacterial and antifungal agents respectively.

引用

页码：144 / 148

页数：5

共 20 条

[1]

[Anonymous], 1964, FATTY ACIDS THEIR CH

[2]

Badami R. C., 1979, J OIL TECHNOL ASS IN, V11, P78

[3] STRUCTURAL MODIFICATION STUDIES OF 3-PIPERONYLSYDNONE .I. SYNTHESIS OF PIPERONYL-SUBSTITUTED PYRAZOLES ISOXAZOLES TRIAZOLES OXADIAZOLES AND THIADIAZOLES (1) [J].