Design of potent inhibitors for human brain memapsin 2 (β-secretase)

[1] BEITH J, 1994, BAYER S, V5, P463

[2] A SHORT, STEREOSELECTIVE SYNTHESIS OF THE LACTONE PRECURSOR TO 2R,4S,5S HYDROXYETHYLENE DIPEPTIDE ISOSTERES [J]. JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (25) : 4828 - 4833

[3] Transition-state mimetics for HIV protease inhibitors: Stereocontrolled synthesis of hydroxyethylene and hydroxyethylamine isosteres by ester-derived titanium enolate syn and anti-aldol reactions [J]. JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (18) : 6146 - 6152

[4] RENIN INHIBITORS [J]. MEDICINAL RESEARCH REVIEWS, 1990, 10 (02) : 173 - 236

[5] Identification of a novel aspartic protease (Asp 2) as β-secretase [J]. MOLECULAR AND CELLULAR NEUROSCIENCE, 1999, 14 (06) : 419 - 427

[6] The penetration of anti-infectives into the central nervous system [J]. NEUROLOGIC CLINICS, 1999, 17 (04) : 883 - +

[7] Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor protein [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (04) : 1456 - 1460

[8] MARCINISZYN J, 1976, J BIOL CHEM, V251, P7088

[9] N-METHOXY-N-METHYLAMIDES AS EFFECTIVE ACYLATING AGENTS [J]. TETRAHEDRON LETTERS, 1981, 22 (39) : 3815 - 3818

[10] Selkoe D. J., 1999, NATURE S, V399A, P23

[1] BEITH J, 1994, BAYER S, V5, P463

[2] A SHORT, STEREOSELECTIVE SYNTHESIS OF THE LACTONE PRECURSOR TO 2R,4S,5S HYDROXYETHYLENE DIPEPTIDE ISOSTERES [J]. JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (25) : 4828 - 4833

[3] Transition-state mimetics for HIV protease inhibitors: Stereocontrolled synthesis of hydroxyethylene and hydroxyethylamine isosteres by ester-derived titanium enolate syn and anti-aldol reactions [J]. JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (18) : 6146 - 6152

[4] RENIN INHIBITORS [J]. MEDICINAL RESEARCH REVIEWS, 1990, 10 (02) : 173 - 236

[5] Identification of a novel aspartic protease (Asp 2) as β-secretase [J]. MOLECULAR AND CELLULAR NEUROSCIENCE, 1999, 14 (06) : 419 - 427

[6] The penetration of anti-infectives into the central nervous system [J]. NEUROLOGIC CLINICS, 1999, 17 (04) : 883 - +

[7] Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor protein [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (04) : 1456 - 1460

[8] MARCINISZYN J, 1976, J BIOL CHEM, V251, P7088

[9] N-METHOXY-N-METHYLAMIDES AS EFFECTIVE ACYLATING AGENTS [J]. TETRAHEDRON LETTERS, 1981, 22 (39) : 3815 - 3818

[10] Selkoe D. J., 1999, NATURE S, V399A, P23