Gains of the proto-oncogene BCL11A and nuclear accumulation of BCL11AXL protein are frequent in primary mediastinal B-cell lymphoma

被引：53
作者：
Weniger, M. A. [1 ]
Pulford, K.
Gesk, S.
Ehrlich, S.
Banham, A. H.
Lyne, L.
Martin-Subero, J. I.
Siebert, R.
Dyer, M. J. S.
Moeller, P.
Barth, T. F. E.
机构：
[1] Univ Ulm, Dept Pathol, Ulm, Germany
[2] Univ Oxford, Nuffield Dept Clin Lab Sci, Oxford, England
[3] Univ Hosp Schleswig Holstein, Inst Human Genet, Kiel, Germany
[4] Univ Leicester, MRC, Toxicol Unit, Leicester, Leics, England
来源：
LEUKEMIA | 2006年 / 20卷 / 10期
基金：
英国医学研究理事会;
关键词：
INVOLVEMENT; REL;
D O I：
10.1038/sj.leu.2404324
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：1880 / 1882
页数：3
相关论文
共 8 条
[1]   Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression-based survival prediction [J].
Bea, S ;
Zettl, A ;
Wright, G ;
Salaverria, I ;
Jehn, P ;
Moreno, V ;
Burek, C ;
Ott, G ;
Puig, X ;
Yang, LM ;
Lopez-Guillermo, A ;
Chan, WC ;
Greiner, TC ;
Weisenburger, DD ;
Armitage, JO ;
Gascoyne, RD ;
Connors, JM ;
Grogan, TM ;
Braziel, R ;
Fisher, RI ;
Smeland, EB ;
Kvaloy, S ;
Holte, H ;
Delabie, J ;
Simon, R ;
Powell, J ;
Wilson, WH ;
Jaffe, ES ;
Montserrat, E ;
Muller-Hermelink, HK ;
Staudt, LM ;
Campo, E ;
Rosenwald, A .
BLOOD, 2005, 106 (09) :3183-3190
[2]   Clinicopathologic significance and prognostic value of chromosomal imbalances in diffuse large B-Cell lymphomas [J].
Beà, S ;
Colomo, L ;
López-Guillermo, AL ;
Salaverria, I ;
Puig, X ;
Pinyol, M ;
Rives, S ;
Montserrat, E ;
Campo, E .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (17) :3498-3506
[3]   Bcl11a is essential for normal lymphoid development [J].
Liu, PT ;
Keller, JR ;
Ortiz, M ;
Tessarollo, L ;
Rachel, RA ;
Nakamura, T ;
Jenkins, NA ;
Copeland, NG .
NATURE IMMUNOLOGY, 2003, 4 (06) :525-532
[4]   Epstein-Barr virus is integrated between REL and BCL-11A in American Burkitt lymphoma cell line (NAB-2) [J].
Luo, WJ ;
Takakuwa, T ;
Ham, MF ;
Wada, N ;
Liu, A ;
Fujita, S ;
Sakane-Ishikawa, E ;
Aozasa, K .
LABORATORY INVESTIGATION, 2004, 84 (09) :1193-1199
[5]   Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma [J].
Martín-Subero, JI ;
Gesk, S ;
Harder, L ;
Sonoki, T ;
Tucker, PW ;
Schlegelberger, B ;
Grote, W ;
Novo, FJ ;
Calasanz, MJ ;
Hansmann, ML ;
Dyer, MJS ;
Siebert, R .
BLOOD, 2002, 99 (04) :1474-1477
[6]  
PULFORD K, 2006, IN PRESS LEUKEMIA
[7]   The BCL11 gene family:: involvement of BCL11A in lymphoid malignancies [J].
Satterwhite, E ;
Sonoki, T ;
Willis, TG ;
Harder, L ;
Nowak, R ;
Arriola, EL ;
Liu, H ;
Price, HP ;
Gesk, S ;
Steinemann, D ;
Schlegelberger, B ;
Oscier, DG ;
Siebert, R ;
Tucker, PW ;
Dyer, MJS .
BLOOD, 2001, 98 (12) :3413-3420
[8]   Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression [J].
Senawong, T ;
Peterson, VJ ;
Avram, D ;
Shepherd, DM ;
Frye, RA ;
Minucci, S ;
Leid, M .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (44) :43041-43050
1