Update on the pathologic diagnosis of chronic myelomonocytic leukemia

被引:17
作者
Arber, Daniel A. [1 ]
Orazi, Attilio [2 ]
机构
[1] Univ Chicago, Dept Pathol, 5841 S Maryland Ave, Chicago, IL 60637 USA
[2] Texas Tech Hlth Sci Ctr, Dept Pathol, El Paso, TX USA
关键词
AGE-RELATED MUTATIONS; PRIMARY MYELOFIBROSIS; CLONAL HEMATOPOIESIS; RISK STRATIFICATION; MYELOID NEOPLASMS; MONOCYTOSIS; SURVIVAL; FEATURES; CLASSIFICATION; ACCUMULATION;
D O I
10.1038/s41379-019-0215-y
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The diagnostic criteria for chronic myelomonocytic leukemia were recently revised in the 2016 World Health Organization classification update and include new and revised subtypes. In addition, molecular genetic studies have provided new insights into the prognosis and diagnosis of this myeloid neoplasm. This review summarizes the 2016 changes to the diagnostic criteria, discusses potential future changes that may impact diagnosis and provides an overview of recent advances in the diagnosis and prognosis determination of chronic myelomonocytic leukemia.
引用
收藏
页码:732 / 740
页数:9
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