Pancreas retransplantation: Outcomes of 20 cases

被引:14
作者
Genzini, T. [1 ]
Crescentini, F. [1 ]
Torricelli, F. C. M. [1 ]
Antunes, I. [1 ]
Hayashi, A. [1 ]
Kim, N. J. [1 ]
Belieacqua, E. R. [1 ]
Noujaim, H. [1 ]
de Sa, J. R. [1 ]
Perosa, M. [1 ]
机构
[1] Albert Einstein Hosp, HEPATO, Hepatol & Organ Transplantat Dept, Sao Paulo, Brazil
关键词
D O I
10.1016/j.transproceed.2006.06.055
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The objective of this paper was to evaluate our initial experience with pancreas retransplantation. From January 26, 1996 to February 2005, 285 pancreas transplantations were performed, including 20 (7%) retransplants. The causes of primary graft loss were graft thrombosis in 11 (55%, 7 venous and 4 arterial); 4 (20%) chronic rejections; 2 (10%) ischemia/reperfusion injury; 1 severe graft pancreatitis; 1 primary nonfunction; and 1 sepsis. Venous drainage was placed in the iliac vessels in 14 (70%), vena-cava in 5 (25%), and portal drainage in 1. The exocrine drainage was vesical in 16 (80%) and enteric in 4 (20%). In 14 cases (70%), the primary graft was removed before and in 6 (30%) at the time of retransplantation. Immunosuppression was based on antilymphocyte induction, tacrolimus, mycophenolate mofetil, and steroids in all patients. One-year patient and graft survivals were 95% and 85%. In conclusion, pancreas retransplants were feasible with results comparable to a primary pancreas transplantation.
引用
收藏
页码:1937 / 1938
页数:2
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