Polypharmacy in the Elderly: Focus on Drug Interactions and Adherence in Hypertension

被引:43
作者
Cooney, Danielle [1 ]
Pascuzzi, Kristina [1 ]
机构
[1] Louis Stokes Vet Affairs Med Ctr, Dept Pharm, Pharm Serv 119W, Cleveland, OH 44106 USA
关键词
Polypharmacy; Adherence; Hypertension; Medication; Elderly; Geriatric; MEDICATION ADHERENCE; THERAPY; AGE;
D O I
10.1016/j.cger.2009.01.005
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Polypharmacy is highly prevalent in the elderly due to an increased number of co-morbid disease states that accompany aging. Hypertension is one common disease that can be challenging to treat in the elderly due to the body's physiologic changes, potential risks for side effects, medication interactions, and decreased medication adherence. A thorough medication assessment for each patient is essential when determining pharmacotherapeutic options in the elderly.
引用
收藏
页码:221 / +
页数:14
相关论文
共 37 条
  • [11] DRUG PRESCRIBING FOR ELDERLY PATIENTS
    CHUTKA, DS
    EVANS, JM
    FLEMING, KC
    MIKKELSON, KG
    [J]. MAYO CLINIC PROCEEDINGS, 1995, 70 (07) : 685 - 693
  • [12] CLONIDINE, 2008, LEXI DRUGS ONLINE
  • [13] MORBIDITY AND MORTALITY IN THE SWEDISH TRIAL IN OLD PATIENTS WITH HYPERTENSION (STOP-HYPERTENSION)
    DAHLOF, B
    LINDHOLM, LH
    HANSSON, L
    SCHERSTEN, B
    EKBOM, T
    WESTER, PO
    [J]. LANCET, 1991, 338 (8778) : 1281 - 1285
  • [14] Duthie E.H., 1998, PRACTICE GERIATRICS, V3e
  • [15] ELLIOTT DP, 2004, PHARMACOTHERAPY SELF, P115
  • [16] Updating the beers criteria for potentially inappropriate medication use in older adults - Results of a US consensus panel of experts
    Fick, DM
    Cooper, JW
    Wade, WE
    Waller, JL
    Maclean, JR
    Beers, MH
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2003, 163 (22) : 2716 - 2724
  • [17] Furberg CD, 2000, JAMA-J AM MED ASSOC, V283, P1967
  • [18] Drug-drug and drug-disease interactions in the ED: Analysis of a high-risk population
    Goldberg, RM
    Mabee, J
    Chan, L
    Wong, S
    [J]. AMERICAN JOURNAL OF EMERGENCY MEDICINE, 1996, 14 (05) : 447 - 450
  • [19] Hansen K., 2005, Pharmacotherapy, V6, P1685
  • [20] Increasing use of medicines in elderly persons:: a five-year follow-up of the Kuoplo 75+Study
    Jyrkkä, J
    Vartiainen, L
    Hartikainen, S
    Sulkava, R
    Enlund, H
    [J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2006, 62 (02) : 151 - 158