Polypharmacy in the Elderly: Focus on Drug Interactions and Adherence in Hypertension

被引：43

作者：

Cooney, Danielle ^{[1
]}

Pascuzzi, Kristina ^{[1
]}

机构：

[1] Louis Stokes Vet Affairs Med Ctr, Dept Pharm, Pharm Serv 119W, Cleveland, OH 44106 USA

来源：

CLINICS IN GERIATRIC MEDICINE | 2009年 / 25卷 / 02期

关键词：

Polypharmacy; Adherence; Hypertension; Medication; Elderly; Geriatric; MEDICATION ADHERENCE; THERAPY; AGE;

D O I：

10.1016/j.cger.2009.01.005

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Polypharmacy is highly prevalent in the elderly due to an increased number of co-morbid disease states that accompany aging. Hypertension is one common disease that can be challenging to treat in the elderly due to the body's physiologic changes, potential risks for side effects, medication interactions, and decreased medication adherence. A thorough medication assessment for each patient is essential when determining pharmacotherapeutic options in the elderly.

引用

页码：221 / +

页数：14

共 37 条

[1]

*2005 JOINT COMM A, 2005, 2005 HOSP NAT PAT SA

[2]

[Anonymous], 1991, JAMA, V265, P3255

[3]

[Anonymous], Webster's Dictionary Online

[4]

*ASTRAZENECA PHARM, 2005, PROD INF TENORMIN

[5] Predictors of medication adherence in the elderly - Commentary [J].

Balkrishnan, R .

CLINICAL THERAPEUTICS, 1998, 20 (04) :764-771

[6] Treatment of hypertension in patients 80 years of age or older [J].

Beckett, Nigel S. ;

Peters, Ruth ;

Fletcher, Astrid E. ;

Staessen, Jan A. ;

Liu, Lisheng ;

Dumitrascu, Dan ;

Stoyanovsky, Vassil ;

Antikainen, Riitta L. ;

Nikitin, Yuri ;

Anderson, Craig ;

Belhani, Alli ;

Forette, Francoise ;

Rajkumar, Chakravarthi ;

Thijs, Lutgarde ;

Banya, Winston ;

Bulpitt, Christopher J. .

NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (18) :1887-1898

[7]

Benet L., 1996, PHARM BASIS THERAPY, V9, P3

[8] Principles of drug therapy for the elderly patient [J].

Bressler, R ;

Bahl, JJ .

MAYO CLINIC PROCEEDINGS, 2003, 78 (12) :1564-1577

[9] Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure [J].

Chobanian, AV ;

Bakris, GL ;

Black, HR ;

Cushman, WC ;

Green, LA ;

Izzo, JL ;

Jones, DW ;

Materson, BJ ;

Oparil, S ;

Wright, JT ;

Roccella, EJ .

HYPERTENSION, 2003, 42 (06) :1206-1252

[10] Inappropriate medications for elderly patients [J].

Chutka, DS ;

Takahashi, PY ;

Hoel, RW .

MAYO CLINIC PROCEEDINGS, 2004, 79 (01) :122-139

← 1 2 3 4 →