Polypharmacy in the Elderly: Focus on Drug Interactions and Adherence in Hypertension

被引:43
作者
Cooney, Danielle [1 ]
Pascuzzi, Kristina [1 ]
机构
[1] Louis Stokes Vet Affairs Med Ctr, Dept Pharm, Pharm Serv 119W, Cleveland, OH 44106 USA
关键词
Polypharmacy; Adherence; Hypertension; Medication; Elderly; Geriatric; MEDICATION ADHERENCE; THERAPY; AGE;
D O I
10.1016/j.cger.2009.01.005
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Polypharmacy is highly prevalent in the elderly due to an increased number of co-morbid disease states that accompany aging. Hypertension is one common disease that can be challenging to treat in the elderly due to the body's physiologic changes, potential risks for side effects, medication interactions, and decreased medication adherence. A thorough medication assessment for each patient is essential when determining pharmacotherapeutic options in the elderly.
引用
收藏
页码:221 / +
页数:14
相关论文
共 37 条
  • [1] *2005 JOINT COMM A, 2005, 2005 HOSP NAT PAT SA
  • [2] [Anonymous], 1991, JAMA, V265, P3255
  • [3] [Anonymous], Webster's Dictionary Online
  • [4] *ASTRAZENECA PHARM, 2005, PROD INF TENORMIN
  • [5] Predictors of medication adherence in the elderly - Commentary
    Balkrishnan, R
    [J]. CLINICAL THERAPEUTICS, 1998, 20 (04) : 764 - 771
  • [6] Treatment of hypertension in patients 80 years of age or older
    Beckett, Nigel S.
    Peters, Ruth
    Fletcher, Astrid E.
    Staessen, Jan A.
    Liu, Lisheng
    Dumitrascu, Dan
    Stoyanovsky, Vassil
    Antikainen, Riitta L.
    Nikitin, Yuri
    Anderson, Craig
    Belhani, Alli
    Forette, Francoise
    Rajkumar, Chakravarthi
    Thijs, Lutgarde
    Banya, Winston
    Bulpitt, Christopher J.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (18) : 1887 - 1898
  • [7] Benet L., 1996, PHARM BASIS THERAPY, V9, P3
  • [8] Principles of drug therapy for the elderly patient
    Bressler, R
    Bahl, JJ
    [J]. MAYO CLINIC PROCEEDINGS, 2003, 78 (12) : 1564 - 1577
  • [9] Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    Chobanian, AV
    Bakris, GL
    Black, HR
    Cushman, WC
    Green, LA
    Izzo, JL
    Jones, DW
    Materson, BJ
    Oparil, S
    Wright, JT
    Roccella, EJ
    [J]. HYPERTENSION, 2003, 42 (06) : 1206 - 1252
  • [10] Inappropriate medications for elderly patients
    Chutka, DS
    Takahashi, PY
    Hoel, RW
    [J]. MAYO CLINIC PROCEEDINGS, 2004, 79 (01) : 122 - 139