Sulfuric acid promoted condensation cyclization of 2-(2-(trimethylsilyl) ethynyl)anilines with arylaldehydes in alcoholic solvents: an efficient one-pot synthesis of 4-alkoxy-2-arylquinolines

被引：32

作者：

Wang, Yong ^{[1
]}

Peng, Changlan ^{[1
]}

Liu, Lanying ^{[1
]}

Zhao, Jiaji ^{[1
]}

Su, Li ^{[1
]}

Zhu, Qiang ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Biol Chem, Guangzhou Inst Biomed & Hlth, Guangzhou 510663, Guangdong, Peoples R China

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 19期

关键词：

INDIRECT FRIEDLANDER SYNTHESIS; SUBSTITUTED QUINOLINES; 2,4-DISUBSTITUTED QUINOLINES; OXIDATIVE CYCLIZATION; RECENT PROGRESS; IN-VITRO; DERIVATIVES; 2-ARYL-1,2,3,4-TETRAHYDRO-4-QUINOLONES; 2-ARYLQUINOLINE; ANTIBACTERIAL;

D O I：

10.1016/j.tetlet.2009.02.206

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient method for the synthesis of 4-alkoxy-2-arylquinolines has been developed. The reaction proceeds smoothly by heating a mixture of easily accessible 2-(2-(trimethylsilyl) ethynyl)anilines and arylaldehydes in alcoholic solvents in the presence of sulfuric acid. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2261 / 2265

页数：5

共 58 条

[51] In vitro antifungal activity of new series of homoallylamines and related compounds with inhibitory properties of the synthesis of fungal cell wall polymers [J].