Selective activation of the sympathetic ganglia by centrally administered corticotropin-releasing factor in rats

被引：11

作者：

Usui, Daisuke ^{[1
,2
]}

Yamaguchi-Shima, Naoko ^{[1
]}

Okada, Shoshiro ^{[1
]}

Shimizu, Takahiro ^{[1
]}

Wakiguchi, Hiroshi ^{[2
]}

Yokotani, Kunihiko ^{[1
]}

机构：

[1] Kochi Univ, Sch Med, Dept Pharmacol, Nanko Ku, Kochi 7838505, Japan

[2] Kochi Univ, Sch Med, Dept Pediat, Nanko Ku, Kochi 7838505, Japan

来源：

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL | 2009年 / 146卷 / 1-2期

关键词：

Corticotropin-releasing factor; Sympatho-adrenomedullary system; Sympathetic ganglion; c-Fos; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; ADRENAL EPINEPHRINE SECRETION; AUTONOMIC NERVOUS-SYSTEM; SPINAL-CORD; PREGANGLIONIC NEURONS; GENE-EXPRESSION; RECEPTOR; HORMONE; OUTFLOW; BRAIN;

D O I：

10.1016/j.autneu.2008.12.008

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The sympathetic efferent pathway projects to the sympathetic ganglia and the adrenal medulla. In this study, we examined centrally administered corticotropin-releasing factor (CRF)-induced neuronal activation of noradrenergic postganglionic neurons in several kinds of the sympathetic ganglia (superior cervical, stellate and celiac ganglia) in anesthetized rats. CRF significantly increased c-Fos expression in the celiac and stellate ganglia, with more pronounced effect on the celiac ganglion. On the other hand, CRF had no effect on c-Fos expression in the superior cervical ganglion even at a higher dose. These results suggest that brain CRF selectively regulates neuronal activity of each sympathetic ganglion. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：111 / 114

页数：4

共 50 条

[21] Intersections of Sex and Corticotropin-Releasing Factor
Gourley, Shannon L.
Taylor, Jane R.
BIOLOGICAL PSYCHIATRY, 2014, 75 (11) : 838 - 839
[22] Corticotropin-releasing factor potentiates glutamatergic input and excitability of presympathetic neurons in the hypothalamus in spontaneously hypertensive rats
Ma, Hongyu
Cui, Ziye
Guo, Xinqi
Zhao, Qiyue
Zhang, Ying
Guan, Yue
Yang, Peiyun
Zhu, Huaibing
Wang, Sheng
Zhang, Xiangjian
Zhang, Yi
Pan, Hui-Lin
Ma, Huijie
NEUROPHARMACOLOGY, 2023, 230
[23] The Contribution of Corticotropin-Releasing Factor to Gastroprotection
L. P. Filaretova
Neurochemical Journal, 2018, 12 : 127 - 129
[24] Anti-sexual and anxiogenic behavioral consequences of corticotropin-releasing factor overexpression are centrally mediated
Heinrichs, SC
Min, H
Tamraz, S
Carmouche, M
Boehme, SA
Vale, WW
PSYCHONEUROENDOCRINOLOGY, 1997, 22 (04) : 215 - 224
[25] The behavioural effects of corticotropin-releasing factor-related peptides in rats
D. N. C. Jones
R. Kortekaas
Paula D. Slade
Derek N. Middlemiss
Jim J. Hagan
Psychopharmacology, 1998, 138 : 124 - 132
[26] Corticotropin-releasing factor receptors and urocortins, links between the brain and the heart
Yang, Li-Zhen
Tovote, Philip
Rayner, Martin
Kockskaemper, Jens
Pieske, Burkert
Spiess, Joachim
EUROPEAN JOURNAL OF PHARMACOLOGY, 2010, 632 (1-3) : 1 - 6
[27] ALTERATION OF CORTICOTROPIN-RELEASING FACTOR IMMUNOREACTIVITY IN MPTP-TREATED RATS
HUANG, CC
LEE, EHY
JOURNAL OF NEUROSCIENCE RESEARCH, 1995, 41 (04) : 471 - 480
[28] Role and action in the pituitary corticotroph of corticotropin-releasing factor (CRF) in the hypothalamus
Kageyama, Kazunori
Suda, Toshihiro
PEPTIDES, 2009, 30 (04) : 810 - 816
[29] Blocking corticotropin-releasing factor-2 receptors, but not corticotropin-releasing factor-1 receptors or glucocorticoid feedback, disrupts the development of conditioned defeat
Cooper, Matthew A.
Huhman, Kim L.
PHYSIOLOGY & BEHAVIOR, 2010, 101 (04) : 527 - 532
[30] Brain nuclear factor kappa B is involved in the corticotropin-releasing factor-induced central activation of sympatho-adrenomedullary outflow in rats
Okada, Shoshiro
Yamaguchi-Shima, Naoko
Shimizu, Takahiro
Arai, Junichi
Yorirnitsu, Mieko
Yokotani, Kunihiko
EUROPEAN JOURNAL OF PHARMACOLOGY, 2008, 584 (01) : 207 - 212

← 1 2 3 4 5 →