Tumor Microenvironment and Immunotherapy: The Whole Picture Is Better Than a Glimpse

被引：44

作者：

Church, Sarah E. ^{[1
,2
,3
]}

Galon, Jerome ^{[1
,2
,3
]}

机构：

[1] INSERM, UMRS1138, Lab Integrat Canc Immunol, F-75006 Paris, France

[2] Univ Paris 05, F-75006 Paris, France

[3] Univ Paris 06, Cordeliers Res Ctr, F-75006 Paris, France

来源：

IMMUNITY | 2015年 / 43卷 / 04期

关键词：

IMMUNE CELLS; CANCER;

D O I：

10.1016/j.immuni.2015.10.004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Predicting cancer patients' response to therapy is essential for curing disease and improving quality of life. Garraway and colleagues demonstrate that the frequency and number of neoantigens, non-synonymous mutations, and adaptive immune genes, but not the assessment of individual recurrent neoantigens or mutations, predicts patient responses to immunotherapy.

引用

页码：631 / 633

页数：4

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