The evaluation and management of respiratory disease in children with Down syndrome (DS)

被引:33
作者
Alsubie, Haya S. [1 ]
Rosen, Dennis [2 ,3 ]
机构
[1] Specialized Med Ctr, Dept Pediat Resp Med, Sleep Disorders Ctr, Box 84350, Riyadh 11671, Saudi Arabia
[2] Harvard Med Sch, Boston, MA USA
[3] Boston Childrens Hosp, Div Resp Dis, 300 Longwood Ave, Boston, MA 02115 USA
关键词
Upper airway obstruction; Adenotonsillectomy; Congenital Heart Disease; Gastroesophageal reflux; Polysomnography; Recurrent wheeze; OBSTRUCTIVE SLEEP-APNEA; MITRAL-VALVE-PROLAPSE; UPPER-AIRWAY STIMULATION; SUBPLEURAL LUNG CYSTS; PULMONARY-HYPERTENSION; AORTIC REGURGITATION; SURGICAL-MANAGEMENT; PEDIATRIC-PATIENTS; TRACHEAL STENOSIS; YOUNG-CHILDREN;
D O I
10.1016/j.prrv.2017.07.003
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Children with Down syndrome (DS) have wide range of respiratory problems. Although underlying abnormalities in the respiratory system are important causes of morbidity and mortality in children with DS, particularly in the young, abnormalities in other organ systems may also impact respiratory function. A comprehensive evaluation of the child with DS and respiratory disease may prevent short-term morbidity and mortality, and reduce the incidence of complications in the long term. This review provides an overview of the various causes of respiratory disease, and insight into some of the newer therapies available to treat obstructive sleep apnea, in this population. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:49 / 54
页数:6
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