The evaluation and management of respiratory disease in children with Down syndrome (DS)

被引：33
作者：
Alsubie, Haya S. [1 ]
Rosen, Dennis [2 ,3 ]
机构：
[1] Specialized Med Ctr, Dept Pediat Resp Med, Sleep Disorders Ctr, Box 84350, Riyadh 11671, Saudi Arabia
[2] Harvard Med Sch, Boston, MA USA
[3] Boston Childrens Hosp, Div Resp Dis, 300 Longwood Ave, Boston, MA 02115 USA
来源：
PAEDIATRIC RESPIRATORY REVIEWS | 2018年 / 26卷
关键词：
Upper airway obstruction; Adenotonsillectomy; Congenital Heart Disease; Gastroesophageal reflux; Polysomnography; Recurrent wheeze; OBSTRUCTIVE SLEEP-APNEA; MITRAL-VALVE-PROLAPSE; UPPER-AIRWAY STIMULATION; SUBPLEURAL LUNG CYSTS; PULMONARY-HYPERTENSION; AORTIC REGURGITATION; SURGICAL-MANAGEMENT; PEDIATRIC-PATIENTS; TRACHEAL STENOSIS; YOUNG-CHILDREN;
D O I：
10.1016/j.prrv.2017.07.003
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Children with Down syndrome (DS) have wide range of respiratory problems. Although underlying abnormalities in the respiratory system are important causes of morbidity and mortality in children with DS, particularly in the young, abnormalities in other organ systems may also impact respiratory function. A comprehensive evaluation of the child with DS and respiratory disease may prevent short-term morbidity and mortality, and reduce the incidence of complications in the long term. This review provides an overview of the various causes of respiratory disease, and insight into some of the newer therapies available to treat obstructive sleep apnea, in this population. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：49 / 54
页数：6
相关论文
共 94 条
[1]  
Al-Harasi SM, 2013, SYNDROME OMAN ETIOLO
[2]   Profile of chromosomal abnormalities in the Al Jahra region of Kuwait [J].
Al-Naggar, RL ;
Mady, SA ;
Tayel, SM ;
Farag, TI ;
Al-Awadia, SA ;
Al-Ghanim, MM ;
Abulhasan, SJ ;
Sabry, MA ;
Bastaki, L .
MEDICAL PRINCIPLES AND PRACTICE, 1999, 8 (03) :167-172
[3]  
ALFI OS, 1980, AM J HUM GENET, V32, P477
[4]  
Amir IM, 2002, AM J HUM GENET, V71, P377
[5]  
[Anonymous], DOWN SYNDR
[6]  
[Anonymous], DOWN SYNDR FACTS
[7]   Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood:: ISAAC Phases One and Three repeat multicountry cross-sectional surveys [J].
Asher, M. Innes ;
Montefort, Stephen ;
Bjorksten, Bengt ;
Lai, Christopher K. W. ;
Strachan, David P. ;
Weiland, Stephan K. ;
Williams, Hywel .
LANCET, 2006, 368 (9537) :733-743
[8]  
Bergstrom S, 2016, PEDIATRICS, P138
[9]   Airway anomalies in children with Down syndrome:: Endoscopic findings [J].
Bertrand, P ;
Navarro, H ;
Caussade, S ;
Holmgren, N ;
Sánchez, I .
PEDIATRIC PULMONOLOGY, 2003, 36 (02) :137-141
[10]   Subpleural lung cysts in Down syndrome: prevalence and association with coexisting diagnoses [J].
Biko, David M. ;
Schwartz, Michael ;
Anupindi, Sudha A. ;
Altes, Talissa A. .
PEDIATRIC RADIOLOGY, 2008, 38 (03) :280-284
12345678910