Two new benzoate derivatives and one new phenylacetate derivative from a marine-derived fungus Engyodontium album

被引:10
作者
Wang, Weiyi [1 ,2 ]
Chen, Ruixuan [1 ]
Luo, Zhuhua [1 ]
Wang, Wei [1 ]
Chen, Jianming [1 ]
机构
[1] State Ocean Adm, Inst Oceanog 3, Fujian Collaborat Innovat Ctr Exploitat & Utiliza, Key Lab Marine Biogenet Resources, Xiamen, Peoples R China
[2] Chinese Acad Sci, Inst Urban Environm, Key Lab Urban Environm & Hlth, Xiamen, Peoples R China
关键词
Engyodontium album; phenylacetate derivative; benzoate derivative; antibacterial; CYTOTOXIC CONSTITUENTS; PHENOLIC-COMPOUNDS; LEAVES;
D O I
10.1080/14786419.2016.1242002
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Two new benzoate derivatives, ethyl 3,5-dimethoxy-2-propionylbenzoate (1) and ethyl 3,5-dihydroxy-2-propionylbenzoate (2), and one new phenylacetate derivative, ethyl 3,5-dimethoxy-2-propionylphenylacetate (3), together with 9 known compounds, were isolated from the fermentation of Engyodontium album derived from deep sea sediment. Their structures were elucidated by spectroscopic techniques, such as NMR, IR and HRESIMS. Compound 3 exhibited inhibitory activities against methicillin-resistant Staphylococcus aureus ATCC 43300 (MRSA) and Vibrio vulnificus, with MIC values of 7.8 and 15.6g/mL, respectively.
引用
收藏
页码:758 / 764
页数:7
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共 11 条
  • [1] Fingerprint Analysis and Simultaneous Determination of Phenolic Compounds in Extracts of Curculiginis Rhizoma by HPLC-Diode Array Detector
    Bian, Qingya
    Yang, Hui
    Chan, Chi-on
    Jin, Dengping
    Mok, Daniel Kam-Wah
    Chen, Sibao
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2013, 61 (08) : 802 - 808
  • [2] 2 NEW COMPOUNDS FROM ARTEMISIA-ANNUA
    BROWN, GD
    [J]. JOURNAL OF NATURAL PRODUCTS, 1992, 55 (12): : 1756 - 1760
  • [3] Cytotoxic constituents of the leaves of Calocedrus formosana
    Chiang, YM
    Liu, HK
    Lo, JM
    Chien, SC
    Chan, Y
    Lee, TH
    Su, JK
    Kuo, YH
    [J]. JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2003, 50 (01) : 161 - 166
  • [4] Unusual phenolic glycosides from Cotoneaster orbicularis
    El-Mousallamy, AMD
    Hussein, SAM
    Merfort, I
    Nawwar, MAM
    [J]. PHYTOCHEMISTRY, 2000, 53 (06) : 699 - 704
  • [5] Pharmacological Properties of the Marine Natural Product Marinopyrrole A against Methicillin-Resistant Staphylococcus aureus
    Haste, Nina M.
    Hughes, Chambers C.
    Tran, Dan N.
    Fenical, William
    Jensen, Paul R.
    Nizet, Victor
    Hensler, Mary E.
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2011, 55 (07) : 3305 - 3312
  • [6] MONOHYDROXY TEREPHTHALIC AND 2,5-DIHYDROXY TEREPHTHALIC ACIDS, 2 UNUSUAL PHENOLICS ISOLATED FROM CENTAURIUM-ERYTHRAEA AND IDENTIFIED IN OTHER GENTIANACEAE MEMBERS
    HATJIMANOLI, M
    FAVREBONVIN, J
    KAOUADJI, M
    MARIOTTE, AM
    [J]. JOURNAL OF NATURAL PRODUCTS, 1988, 51 (05): : 977 - 980
  • [7] Cytotoxic Phenolic Compounds from Chionanthus retusus
    Kwak, Jong Hwan
    Kang, Min Woo
    Roh, Jong Hwa
    Choi, Sang Un
    Zee, Ok Pyo
    [J]. ARCHIVES OF PHARMACAL RESEARCH, 2009, 32 (12) : 1681 - 1687
  • [8] Cytosporone B, an Inhibitor of the Type III Secretion System of Salmonella enterica Serovar Typhimurium
    Li, Jianfang
    Lv, Chao
    Sun, Weiyang
    Li, Zhenyu
    Han, Xiaowei
    Li, Yaoyao
    Shen, Yuemao
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 57 (05) : 2191 - 2198
  • [9] Studies on Cytotoxic Constituents from the Leaves of Elaeagnus oldhamii Maxim. in Non-Small Cell Lung Cancer A549 Cells
    Liao, Chi-Ren
    Kuo, Yueh-Hsiung
    Ho, Yu-Ling
    Wang, Ching-Ying
    Yang, Chang -Syun
    Lin, Cheng-Wen
    Chang, Yuan-Shiun
    [J]. MOLECULES, 2014, 19 (07) : 9515 - 9534
  • [10] Formylation of Electron-Rich Aromatic Rings Mediated by Dichloromethyl Methyl Ether and TiCl4: Scope and Limitations
    Ramos-Tomillero, Ivan
    Paradis-Bas, Marta
    Ribeiro Moreira, Iberio de Pinho
    Maria Bofill, Josep
    Nicolas, Ernesto
    Albericio, Fernando
    [J]. MOLECULES, 2015, 20 (04) : 5409 - 5422