Selective detection of chloramphenicol in milk based on a molecularly imprinted polymer-surface-enhanced Raman spectroscopic nanosensor

被引：41

作者：

Xie, Yunfei ^{[1
]}

Zhao, Mengyao ^{[1
]}

Hu, Qi ^{[1
]}

Cheng, Yuliang ^{[1
]}

Guo, Yahui ^{[1
]}

Qian, He ^{[1
]}

Yao, Weirong ^{[1
]}

机构：

[1] Jiangnan Univ, Sch Food Sci & Technol, State Key Lab Food Sci & Technol, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

来源：

JOURNAL OF RAMAN SPECTROSCOPY | 2017年 / 48卷 / 02期

关键词：

molecularly imprinted polymers (MIP); SERS; chloramphenicol; nanosensor; detection; TANDEM MASS-SPECTROMETRY; SOLID-PHASE EXTRACTION; LIQUID-CHROMATOGRAPHY; HONEY; SCATTERING; SERS; NANOPARTICLES;

D O I：

10.1002/jrs.5034

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

In this study, a novel hybrid molecularly imprinted polymer (MIP) with a surface-enhanced Raman spectroscopy (SERS) sensor was proposed for the detection of chloramphenicol in milk. The MIP was prepared by precipitation polymerization, and the template molecule was extracted by ultrasonic wave. The polymer was placed in a sodium citrate reduction reaction to prepare the chloramphenicol-MIP-Au substrate. The optimal detection conditions were carried out in a mixed solution of methanol and water (1:9). The sensor can be used to detect chloramphenicol in milk samples with a detection limit of 0.1 mu g/ml. The chloramphenicol-MIP-Au substrate served not only as an enrichment medium but also as an enhancement substrate base for SERS detection. Experimental results showed that the MIP hybrid as a SERS platform owned potential for simplifying the detection step and highly selective detection of chloramphenicol in milk. Copyright (c) 2016 John Wiley & Sons, Ltd.

引用

页码：204 / 210

页数：7

共 25 条

[1] Development of an improved method for trace analysis of chloramphenicol using molecularly imprinted polymers [J].