Hypoglycemia in cystic fibrosis: Prevalence, impact and treatment

被引:18
作者
Moheet, Amir [1 ]
Chan, Christine L. [2 ]
Granados, Andrea [3 ]
Ode, Katie Larson [4 ]
Moran, Antoinette [5 ]
Battezzati, Alberto [6 ]
机构
[1] Univ Minnesota, Dept Med, MMC 101,420 Delaware St SE, Minneapolis, MN 55455 USA
[2] Univ Colorado, Childrens Hosp Colorado, Aurora, CO USA
[3] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA
[4] Univ Iowa, Dept Pediat, Stead Family Childrens Hosp, Iowa City, IA 52242 USA
[5] Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA
[6] Univ Milan, Int Ctr Assessment Nutr Status ICANS, Dept Food Environm & Nutr Sci DeFENS, Milan, Italy
关键词
Hypoglycemia; Cystic fibrosis; CFRD; Reactive hypoglycemia;
D O I
10.1016/j.jcf.2019.08.004
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Hypoglycemia is a common and feared complication of insulin therapy. As in type 1 and type 2 diabetes, people with cystic fibrosis related diabetes are also at risk for hypoglycemia related to insulin therapy. Spontaneous hypoglycemia is also common in patients with CF without diabetes, who are not on glucose lowering medications. Spontaneous hypoglycemia in CF may also occur during or after an oral glucose tolerance test. In this review, we will discuss the definition, epidemiology, pathophysiology and impact of hypoglycemia, with a focus on people with cystic fibrosis. We will also review strategies to manage and prevent hypoglycemia. (C) 2019 The Authors. Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society.
引用
收藏
页码:S19 / S24
页数:6
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