Hypoglycemia in cystic fibrosis: Prevalence, impact and treatment

被引：18

作者：

Moheet, Amir ^{[1
]}

Chan, Christine L. ^{[2
]}

Granados, Andrea ^{[3
]}

Ode, Katie Larson ^{[4
]}

Moran, Antoinette ^{[5
]}

Battezzati, Alberto ^{[6
]}

机构：

[1] Univ Minnesota, Dept Med, MMC 101,420 Delaware St SE, Minneapolis, MN 55455 USA

[2] Univ Colorado, Childrens Hosp Colorado, Aurora, CO USA

[3] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA

[4] Univ Iowa, Dept Pediat, Stead Family Childrens Hosp, Iowa City, IA 52242 USA

[5] Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA

[6] Univ Milan, Int Ctr Assessment Nutr Status ICANS, Dept Food Environm & Nutr Sci DeFENS, Milan, Italy

来源：

JOURNAL OF CYSTIC FIBROSIS | 2019年 / 18卷

关键词：

Hypoglycemia; Cystic fibrosis; CFRD; Reactive hypoglycemia;

D O I：

10.1016/j.jcf.2019.08.004

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Hypoglycemia is a common and feared complication of insulin therapy. As in type 1 and type 2 diabetes, people with cystic fibrosis related diabetes are also at risk for hypoglycemia related to insulin therapy. Spontaneous hypoglycemia is also common in patients with CF without diabetes, who are not on glucose lowering medications. Spontaneous hypoglycemia in CF may also occur during or after an oral glucose tolerance test. In this review, we will discuss the definition, epidemiology, pathophysiology and impact of hypoglycemia, with a focus on people with cystic fibrosis. We will also review strategies to manage and prevent hypoglycemia. (C) 2019 The Authors. Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society.

引用

收藏

页码：S19 / S24

页数：6

相关论文

共 62 条

[1] Glucose Concentrations of Less Than 3.0 mmol/L (54 mg/dL) Should Be Reported in Clinical Trials: A Joint Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes [J].

Amiel, Stephanie A. ;

Aschner, Pablo ;

Childs, Belinda ;

Cryer, Philip E. ;

de Galan, Bastiaan E. ;

Heller, Simon R. ;

Gonder-Frederick, Linda ;

Frier, Brian M. ;

Jones, Timothy ;

Khunti, Kamlesh ;

Leiter, Lawrence A. ;

McCrimmon, Rory J. ;

Luo, Yingying ;

Seaquist, Elizabeth R. ;

Vigersky, Robert ;

Zoungas, Sophia .

DIABETES CARE, 2017, 40 (01) :155-157

[2]

[Anonymous], 2010, ANN NY SCI, V1212, P12

[3] Hypoglycaemia in cystic fibrosis in the absence of diabetes: A systematic review [J].

Armaghanian, N. ;

Brand-Miller, J. C. ;

Markovic, T. P. ;

Steinbeck, K. S. .

JOURNAL OF CYSTIC FIBROSIS, 2016, 15 (03) :274-284

[4] Hypoglycaemia in cystic fibrosis: An analysis of a single centre adult cystic fibrosis clinic [J].

Armaghanian, Natasha ;

Markovic, Tania P. ;

Brand-Miller, Jennie C. ;

Bye, Peter T. P. ;

Moriarty, Carmel P. ;

Steinbeck, Kate S. .

JOURNAL OF CYSTIC FIBROSIS, 2018, 17 (04) :542-547

[5]

Bafendse S, 2012, DIABETIC MED, V29, P293

[6] Spontaneous hypoglycemia in patients with cystic fibrosis [J].

Battezzati, A. ;

Battezzati, P. M. ;

Costantini, D. ;

Seia, M. ;

Zazzeron, L. ;

Russo, M. C. ;

Dacco, V. ;

Bertoli, S. ;

Crosignani, A. ;

Colombo, C. .

EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2007, 156 (03) :369-376

[7] Effect of Continuous Glucose Monitoring on Glycemic Control in Adults With Type 1 Diabetes Using Insulin Injections The DIAMOND Randomized Clinical Trial [J].

Beck, Roy W. ;

Riddlesworth, Tonya ;

Ruedy, Katrina ;

Ahmann, Andrew ;

Bergenstal, Richard ;

Haller, Stacie ;

Kollman, Craig ;

Kruger, Davida ;

McGill, Janet B. ;

Polonsky, William ;

Toschi, Elena ;

Wolpert, Howard ;

Price, David .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2017, 317 (04) :371-378

[8] Insulin secretion improves in cystic fibrosis following ivacaftor correction of CFTR: a small pilot study [J].

Bellin, Melena D. ;

Laguna, Theresa ;

Leschyshyn, Janice ;

Regelmann, Warren ;

Dunitz, Jordan ;

Billings, JoAnne ;

Moran, Antoinette .

PEDIATRIC DIABETES, 2013, 14 (06) :417-421

[9] PLASMA-GLUCOSE CONCENTRATIONS AT THE ONSET OF HYPOGLYCEMIC SYMPTOMS IN PATIENTS WITH POORLY CONTROLLED DIABETES AND IN NONDIABETICS [J].

BOYLE, PJ ;

SCHWARTZ, NS ;

SHAH, SD ;

CLUTTER, WE ;

CRYER, PE .

NEW ENGLAND JOURNAL OF MEDICINE, 1988, 318 (23) :1487-1492

[10] Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2019 [J].

Cefalu, William T. ;

Berg, Erika Gebel ;

Saraco, Mindy ;

Petersen, Matthew P. ;

Uelmen, Sacha ;

Robinson, Shamera .

DIABETES CARE, 2019, 42 :S90-S102

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