Uterine Carcinosarcoma in a Young Female: Case Report and Literature Review

被引:1
作者
Soror, Noha N. [1 ]
Woredekal, Daniel [2 ]
Hemrock, Lori [3 ]
Gibson, Gary [4 ]
Bennett, Robert [5 ]
机构
[1] Western Reserve Hlth Educ Neomed, Internal Med, Warren, OH USA
[2] Trumbull Reg Med Ctr, Dept Med, Youngstown, OH USA
[3] Hope Ctr Canc Care, Med Oncol, Warren, OH 44484 USA
[4] Steward Healthcare, Internal Med, Warren, OH USA
[5] Steward Hlth Care, Pathol, Warren, OH USA
关键词
iron deficiency anemia (ida); uterine carcinosarcoma; uterine malignancy; uterine adenocarcinoma; uterine cancer; RISK; SURVIVAL; UTERUS; TUMORS;
D O I
10.7759/cureus.12642
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Uterine carcinosarcoma (USC) is a rare, aggressive primary neoplasm of the Uterus that represents less than 5% of all uterine malignancies. It usually affects older females in their seventh decade. USC disproportionally affects black women more and it has a worse prognosis than other endometrial carcinomas. We present a case of uterine carcinosarcoma in a young Caucasian female who presented with vague symptoms of nausea, vomiting, and severe iron deficiency anemia.
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页数:5
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共 14 条
[1]   Uterine carcinosarcomas and grade 3 endometrioid cancers - Evidence for distinct tumor behavior [J].
Bansal, Nisha ;
Herzog, Thomas J. ;
Seshan, Venkatraman E. ;
Schiff, Peter B. ;
Burke, William M. ;
Cohen, Carmel J. ;
Wright, Jason D. .
OBSTETRICS AND GYNECOLOGY, 2008, 112 (01) :64-70
[2]   Surveillance, Epidemiology, and End Results analysis of 2677 cases of uterine sarcoma 1989-1999 [J].
Brooks, BE ;
Zhan, M ;
Cote, T ;
Baquet, CR .
GYNECOLOGIC ONCOLOGY, 2004, 93 (01) :204-208
[3]   Malignant mixed Mullerian tumors of the uterus: Analysis of patterns of failure, prognostic factors, and treatment outcome [J].
Callister, M ;
Ramondetta, LM ;
Jhingran, A ;
Burke, TW ;
Eifel, PJ .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2004, 58 (03) :786-796
[4]   Uterine carcinosarcoma: A review of the literature [J].
Cantrell, Leigh A. ;
Blank, Stephanie V. ;
Duska, Linda R. .
GYNECOLOGIC ONCOLOGY, 2015, 137 (03) :581-588
[5]   Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial [J].
de Boer, Stephanie M. ;
Powell, Melanie E. ;
Mileshkin, Linda ;
Katsaros, Dionyssios ;
Bessette, Paul ;
Haie-Meder, Christine ;
Ottevanger, Petronella B. ;
Ledermann, Jonathan A. ;
Khaw, Pearly ;
Colombo, Alessandro ;
Fyles, Anthony ;
Baron, Marie-Helene ;
Jurgenliemk-Schulz, Ina M. ;
Kitchener, Henry C. ;
Nijman, Hans W. ;
Wilson, Godfrey ;
Brooks, Susan ;
Carinelli, Silvestro ;
Provencher, Diane ;
Hanzen, Chantal ;
Lutgens, Ludy C. H. W. ;
Smit, Vincent T. H. B. M. ;
Singh, Naveena ;
Do, Viet ;
D'Amico, Romerai ;
Nout, Remi A. ;
Feeney, Amanda ;
Verhoeven-Adema, Karen W. ;
Putter, Hein ;
Creutzberg, Carien L. .
LANCET ONCOLOGY, 2018, 19 (03) :295-309
[6]   Uterine Carcinosarcomas - Diagnosis and Management [J].
Denschlag, Dominik ;
Ulrich, Uwe A. .
ONCOLOGY RESEARCH AND TREATMENT, 2018, 41 (11) :675-679
[7]   Serum CA 125 predicts extrauterine disease and survival in uterine carcinosarcoma [J].
Huang, Gloria S. ;
Chiu, Lydia G. ;
Gebb, Juliana S. ;
Gunter, Marc J. ;
Sukumvanich, Paniti ;
Goldberg, Gary L. ;
Einstein, Mark H. .
GYNECOLOGIC ONCOLOGY, 2007, 107 (03) :513-517
[8]   Addressing the Role of Obesity in Endometrial Cancer Risk, Prevention, and Treatment [J].
Onstad, Michaela A. ;
Schmandt, Rosemarie E. ;
Lu, Karen H. .
JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (35) :4225-+
[9]   Uterine and Ovary Carcinosarcomas Outcome, Prognosis Factors, and Adjuvant Therapy [J].
Pacaut, Cecile ;
Bourmaud, Aurelie ;
Rivoirard, Romain ;
Moriceau, Guillaume ;
Guy, Jean-Baptiste ;
Collard, Olivier ;
Bosacki, Claire ;
Jacquin, Jean-Philippe ;
Levy, Antonin ;
Chauleur, Celine ;
Magne, Nicolas ;
Merrouche, Yacine .
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2015, 38 (03) :272-277
[10]   Phase II Evaluation of Paclitaxel and Carboplatin in the Treatment of Carcinosarcoma of the Uterus: A Gynecologic Oncology Group Study [J].
Powell, Matthew A. ;
Filiaci, Virginia L. ;
Rose, Peter G. ;
Mannel, Robert S. ;
Hanjani, Parviz ;
DeGeest, Koen ;
Miller, Brigitte E. ;
Susumu, Nobuyuki ;
Ueland, Frederick R. .
JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (16) :2727-2731