Progeria: a perspective on potential drug targets and treatment strategies

被引：2
|
作者：
Benedicto, Ignacio [1 ]
Chen, Xue [2 ]
Bergo, Martin O. [3 ]
Andres, Vicente [1 ,4 ]
机构：
[1] Ctr Nacl Invest Cardiovasc Carlos III CNIC, New Mech Atherosclerosis Program, Madrid, Spain
[2] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Plast & Cosmet Surg, Wuhan, Huazhong, Peoples R China
[3] Karolinska Inst, Dept Biosci & Nutr, Huddinge, Sweden
[4] CIBER Enfermedades Cardiovasc CIBERCV, Madrid, Spain
来源：
EXPERT OPINION ON THERAPEUTIC TARGETS | 2022年 / 26卷 / 05期
基金：
瑞典研究理事会;
关键词：
Hutchinson-Gilford progeria syndrome; farnesyltransferase (FTase); isoprenylcysteine carboxyl methyltransferase (ICMT); antisense oligonucleotide (ASO); gene editing; CRISPR/Cas9; adenine base editor (ABE); THERAPEUTIC ANTISENSE OLIGONUCLEOTIDES; MOUSE MODEL; FARNESYLTRANSFERASE INHIBITOR; FARNESYLATION INHIBITORS; VASCULAR CALCIFICATION; EXTENDS LONGEVITY; CLINICAL-TRIAL; DISEASE; ACTIVATION; PRELAMIN;
D O I：
10.1080/14728222.2022.2078699
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：393 / 399
页数：7
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