Current status of accurate prognostic awareness in advanced/terminally ill cancer patients: Systematic review and meta-regression analysis

被引:118
作者
Chen, Chen Hsiu [1 ,2 ]
Kuo, Su Ching [2 ,3 ]
Tang, Siew Tzuh [4 ,5 ,6 ]
机构
[1] Univ Kang Ning, Dept Nursing, Tainan, Taiwan
[2] Chang Gung Univ, Grad Inst Clin Med Sci, Taoyuan, Taiwan
[3] Yuanpei Univ, Dept Nursing, Hsinchu, Taiwan
[4] Chang Gung Univ, Sch Nursing, Coll Med, 259 Wen Hua 1st Rd, Taoyuan 333, Taiwan
[5] Chang Gung Mem Hosp, Dept Nursing, Kaohsiung, Taiwan
[6] Chang Gung Mem Hosp, Div Hematol Oncol, Taoyuan, Taiwan
关键词
Prognosis; awareness; accurate prognostic awareness; neoplasms; QUALITY-OF-LIFE; PALLIATIVE CARE; TERMINAL ILLNESS; DISEASE STATUS; INFORMATION PREFERENCES; COMMUNICATING PROGNOSIS; FAMILY CAREGIVER; DECISION-MAKING; END; EXPECTATIONS;
D O I
10.1177/0269216316663976
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Background: No systematic meta-analysis is available on the prevalence of cancer patients' accurate prognostic awareness and differences in accurate prognostic awareness by publication year, region, assessment method, and service received. Aim: To examine the prevalence of advanced/terminal cancer patients' accurate prognostic awareness and differences in accurate prognostic awareness by publication year, region, assessment method, and service received. Design: Systematic review and meta-analysis. Methods: MEDLINE, Embase, The Cochrane Library, CINAHL, and PsycINFO were systematically searched on accurate prognostic awareness in adult patients with advanced/terminal cancer (1990-2014). Pooled prevalences were calculated for accurate prognostic awareness by a random-effects model. Differences in weighted estimates of accurate prognostic awareness were compared by meta-regression. Results: In total, 34 articles were retrieved for systematic review and meta-analysis. At best, only about half of advanced/terminal cancer patients accurately understood their prognosis (49.1%; 95% confidence interval: 42.7%-55.5%; range: 5.4%-85.7%). Accurate prognostic awareness was independent of service received and publication year, but highest in Australia, followed by East Asia, North America, and southern Europe and the United Kingdom (67.7%, 60.7%, 52.8%, and 36.0%, respectively; p=0.019). Accurate prognostic awareness was higher by clinician assessment than by patient report (63.2% vs 44.5%, p<0.001). Conclusion: Less than half of advanced/terminal cancer patients accurately understood their prognosis, with significant variations by region and assessment method. Healthcare professionals should thoroughly assess advanced/terminal cancer patients' preferences for prognostic information and engage them in prognostic discussion early in the cancer trajectory, thus facilitating their accurate prognostic awareness and the quality of end-of-life care decision-making.
引用
收藏
页码:406 / 418
页数:13
相关论文
共 81 条
[1]   THE EUROPEAN-ORGANIZATION-FOR-RESEARCH-AND-TREATMENT-OF-CANCER QLQ-C30 - A QUALITY-OF-LIFE INSTRUMENT FOR USE IN INTERNATIONAL CLINICAL-TRIALS IN ONCOLOGY [J].
AARONSON, NK ;
AHMEDZAI, S ;
BERGMAN, B ;
BULLINGER, M ;
CULL, A ;
DUEZ, NJ ;
FILIBERTI, A ;
FLECHTNER, H ;
FLEISHMAN, SB ;
DEHAES, JCJM ;
KAASA, S ;
KLEE, M ;
OSOBA, D ;
RAZAVI, D ;
ROFE, PB ;
SCHRAUB, S ;
SNEEUW, K ;
SULLIVAN, M ;
TAKEDA, F .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1993, 85 (05) :365-376
[2]   The impact of awareness of terminal illness on quality of death and care decision making: a prospective nationwide survey of bereaved family members of advanced cancer patients [J].
Ahn, Eunmi ;
Shin, Dong Wook ;
Choi, Jin Young ;
Kang, Jina ;
Kim, Dae Kyun ;
Kim, Hyesuk ;
Lee, Eunil ;
Hwang, Kwan Ok ;
Oh, Bumjo ;
Cho, BeLong .
PSYCHO-ONCOLOGY, 2013, 22 (12) :2771-2778
[3]   Can This Patient Be Discharged Home? Factors Associated With At-Home Death Among Patients With Cancer [J].
Alonso-Babarro, Alberto ;
Bruera, Eduardo ;
Varela-Cerdeira, Maria ;
Jesus Boya-Cristia, Maria ;
Madero, Rosario ;
Torres-Vigil, Isabel ;
De Castro, Javier ;
Gonzalez-Baron, Manuel .
JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (09) :1159-1167
[4]   Illness awareness of patients in hospice: Psychological evaluation and perception of family members and medical staff [J].
Andruccioli, Jessica ;
Montesi, Alessandra ;
Raffaeli, William ;
Monterubbianesi, Maria C. ;
Turci, Paola ;
Pittureri, Cristina ;
Sarti, Donatella ;
Vignali, Alberto P. ;
Rossi, Andrea P. .
JOURNAL OF PALLIATIVE MEDICINE, 2007, 10 (03) :741-748
[5]  
[Anonymous], 2004, Standard quality assessment criteria for evaluating primary research papers from a variety of fields. (HTA Initiative #13), DOI DOI 10.7939/R37M04F16
[6]   Conceptualizing prognostic awareness in advanced cancer: A systematic review [J].
Applebaum, Allison J. ;
Kolva, Elissa A. ;
Kulikowski, Julia R. ;
Jacobs, Jordana D. ;
DeRosa, Antonio ;
Lichtenthal, Wendy G. ;
Olden, Megan E. ;
Rosenfeld, Barry ;
Breitbart, William .
JOURNAL OF HEALTH PSYCHOLOGY, 2014, 19 (09) :1103-1119
[7]   Effect of advanced cancer patients' awareness of disease status on treatment decisional conflicts and satisfaction during palliative chemotherapy: a Korean prospective cohort study [J].
Baek, Sun Kyung ;
Kim, Si-young ;
Heo, Dae Seog ;
Yun, Young Ho ;
Lee, Myung Kyung .
SUPPORTIVE CARE IN CANCER, 2012, 20 (06) :1309-1316
[8]   Does it hurt to know the worst? Psychological morbidity, information preferences and understanding of prognosis in patients with advanced cancer [J].
Barnett, MM .
PSYCHO-ONCOLOGY, 2006, 15 (01) :44-55
[9]   Communication About Serious Illness Care Goals A Review and Synthesis of Best Practices [J].
Bernacki, Rachelle E. ;
Block, Susan D. .
JAMA INTERNAL MEDICINE, 2014, 174 (12) :1994-2003
[10]   Information to cancer patients: a questionnaire survey in three different geographical areas in Italy [J].
Bracci, R. ;
Zanon, E. ;
Cellerino, R. ;
Gesuita, R. ;
Puglisi, F. ;
Aprile, G. ;
Barbieri, V. ;
Misuraca, D. ;
Venuta, S. ;
Carle, F. ;
Piga, A. .
SUPPORTIVE CARE IN CANCER, 2008, 16 (08) :869-877