Development of mobile phone based transcutaneous bilirubinometry

被引:2
作者
Dumont, Alexander P. [1 ]
Harrison, Brandon [1 ]
McCormick, Zachary. T. [1 ]
Kumar, Nishant Ganesh [2 ]
Patil, Chetan A. [1 ]
机构
[1] Temple Univ, Bioengn Dept, 1947 North 12th St, Philadelphia, PA 19122 USA
[2] Vanderbilt Univ, Sch Med, 2215 Garland Ave, Nashville, TN 37232 USA
来源
OPTICS AND BIOPHOTONICS IN LOW-RESOURCE SETTINGS III | 2017年 / 10055卷
关键词
Monte Carlo; diffuse reflectance; spectroscopy; transcutaneous bilirubinometry; mobile phone; TISSUE OPTICAL-PROPERTIES; KUBELKA-MUNK THEORY; DIFFUSE-REFLECTANCE SPECTROSCOPY; TRANS-CUTANEOUS BILIRUBINOMETRY; MONTE-CARLO-SIMULATION; TURBID MEDIA; MULTILAYERED TISSUES; SERUM BILIRUBIN; INVERSE MODEL; LIGHT;
D O I
10.1117/12.2257428
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Infants in the US are routinely screened for risk of neurodevelopmental impairment due to neonatal jaundice using transcutaneous bilirubinometry (TcB). In low-resource settings, such as sub-Saharan Africa, TcB devices are not common, however, mobile camera-phones are now widespread. We provide an update on the development of TcB using the built-in camera and flash of a mobile phone, along with a snap-on adapter containing optical filters. We will present Monte Carlo Extreme modeling of diffuse reflectance in neonatal skin, implications in design, and refined analysis methods.
引用
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页数:12
相关论文
共 35 条
[1]   STANDARD NORMAL VARIATE TRANSFORMATION AND DE-TRENDING OF NEAR-INFRARED DIFFUSE REFLECTANCE SPECTRA [J].
BARNES, RJ ;
DHANOA, MS ;
LISTER, SJ .
APPLIED SPECTROSCOPY, 1989, 43 (05) :772-777
[2]   USE OF THE KUBELKA-MUNK THEORY TO STUDY THE INFLUENCE OF IRON-OXIDES ON SOIL COLOR [J].
BARRON, V ;
TORRENT, J .
JOURNAL OF SOIL SCIENCE, 1986, 37 (04) :499-510
[3]   Predictive ability of a predischarge hour-specific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns [J].
Bhutani, VK ;
Johnson, L ;
Sivieri, EM .
PEDIATRICS, 1999, 103 (01) :6-14
[4]   Noninvasive measurement of total serum bilirubin in a multiracial predischarge newborn population to assess the risk of severe hyperbilirubinemia [J].
Bhutani, VK ;
Gourley, GR ;
Adler, S ;
Kreamer, B ;
Dalin, C ;
Johnson, LH .
PEDIATRICS, 2000, 106 (02) :E17
[5]  
Delgado Atencio J. A., 2011, MONTE CARLO MODELING
[6]   The determination of in vivo human tissue optical properties and absolute chromophore concentrations using spatially resolved steady-state diffuse reflectance spectroscopy [J].
Doornbos, RMP ;
Lang, R ;
Aalders, MC ;
Cross, FW ;
Sterenborg, HJCM .
PHYSICS IN MEDICINE AND BIOLOGY, 1999, 44 (04) :967-981
[7]   Mesh-based Monte Carlo method using fast ray-tracing in Plucker coordinates [J].
Fang, Qianqian .
BIOMEDICAL OPTICS EXPRESS, 2010, 1 (01) :165-175
[8]   Monte Carlo Simulation of Photon Migration in 3D Turbid Media Accelerated by Graphics Processing Units [J].
Fang, Qianqian ;
Boas, David A. .
OPTICS EXPRESS, 2009, 17 (22) :20178-20190
[9]   MONTE-CARLO MODELING OF LIGHT-PROPAGATION IN HIGHLY SCATTERING TISSUES .1. MODEL PREDICTIONS AND COMPARISON WITH DIFFUSION-THEORY [J].
FLOCK, ST ;
PATTERSON, MS ;
WILSON, BC ;
WYMAN, DR .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1989, 36 (12) :1162-1168
[10]   A New Concept for Medical Imaging Centered on Cellular Phone Technology [J].
Granot, Yair ;
Ivorra, Antoni ;
Rubinsky, Boris .
PLOS ONE, 2008, 3 (04)