Outbreak of infections caused by Pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece

被引：225

作者：

Tsakris, A ^{[1
]}

Pournaras, S

Woodford, N

Palepou, AFI

Babini, GS

Douboyas, J

Livermore, DM

机构：

[1] Aristotelian Univ Salonika, Sch Med, Dept Microbiol, GR-54006 Salonika, Greece

[2] AHEPA Univ Hosp, Dept Microbiol, Salonika 54636, Greece

[3] Cent Publ Hlth Lab, Antibiot Resistance Monitoring & Reference Lab, London NW9 5HT, England

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2000年 / 38卷 / 03期

关键词：

D O I：

10.1128/JCM.38.3.1290-1292.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Resistance to imipenem and meropenem was observed in 211 (16.5%) isolates of Pseudomonas aeruginosa recovered in a Greek university hospital during 1996 to 1998. In six isolates selected from throughout this period, high-level resistance to both carbapenems (MICs greater than or equal to 128 mu g/ml) was associated with production of the class B beta-lactamase VLM-1. bla(VIM)-bearing isolates belonged to serotype O:12 and were indistinguishable by pulsed-field gel electrophoresis.

引用

页码：1290 / 1292

页数：3

共 20 条

[1] A NOVEL INTEGRON-LIKE ELEMENT CARRYING THE METALLO-BETA-LACTAMASE GENE BLA(IMP) [J].

ARAKAWA, Y ;

MURAKAMI, M ;

SUZUKI, K ;

ITO, H ;

WACHAROTAYANKUN, R ;

OHSUKA, S ;

KATO, N ;

OHTA, M .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (07) :1612-1615

[2] Metallo-β-lactamases:: A class apart [J].

Bush, K .

CLINICAL INFECTIOUS DISEASES, 1998, 27 :S48-S53

[3] Appearance of IMP-1 metallo-β-lactamase in Europe [J].

Cornaglia, G ;

Riccio, ML ;

Mazzariol, A ;

Lauretti, L ;

Fontana, R ;

Rossolini, GM .

LANCET, 1999, 353 (9156) :899-900

[4] PROPERTIES OF R-PLASMIDS DETERMINING GENTAMICIN RESISTANCE BY ACETYLATION IN PSEUDOMONAS-AERUGINOSA [J].

JACOBY, GA .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1974, 6 (03) :239-252

[5] Carbapenem-hydrolysing IMP-1 β-lactamase in Klebsiella pneumoniae from Singapore [J].

Koh, TH ;

Babini, GS ;

Woodford, N ;

Sng, LH ;

Hall, LMC ;

Livermore, DM .

LANCET, 1999, 353 (9170) :2162-2162

[6] Cloning and characterization of blaVIM, a new integron-borne metallo-β-lactamase gene from a Pseudomonas aeruginosa clinical isolate [J].

Lauretti, L ;

Riccio, ML ;

Mazzariol, A ;

Cornaglia, G ;

Amicosante, G ;

Fontana, R ;

Rossolini, GM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (07) :1584-1590

[7] ON THE INCIDENCE OF ANTIBIOTIC-RESISTANCE AMONG AEROBIC GRAM-NEGATIVE RODS ISOLATED IN GREEK HOSPITALS [J].

LEGAKIS, NJ ;

TZOUVELEKIS, LS ;

TSAKRIS, A ;

LEGAKIS, JN ;

VATOPOULOS, AC .

JOURNAL OF HOSPITAL INFECTION, 1993, 24 (03) :233-237

[8] PCR MAPPING OF INTEGRONS REVEALS SEVERAL NOVEL COMBINATIONS OF RESISTANCE GENES [J].

LEVESQUE, C ;

PICHE, L ;

LAROSE, C ;

ROY, PH .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (01) :185-191

[9]

Livermore D.M., 1996, ANTIBIOTICS LAB MED, P502

[10] BETA-LACTAMASES IN LABORATORY AND CLINICAL RESISTANCE [J].

LIVERMORE, DM .

CLINICAL MICROBIOLOGY REVIEWS, 1995, 8 (04) :557-&

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