Synthesis, Spectroscopic and Structural Studies of New 2-Substituted 4-Nitroimidazoles

被引：3

作者：

Alliouche, Hayette ^{[1
]}

Bouraiou, Abdelmalek ^{[1
]}

Bouacida, Sofiane ^{[2
]}

Bahnous, Mebarek ^{[1
]}

Roisnel, Thierry ^{[3
]}

Belfaitah, Ali ^{[1
]}

机构：

[1] Univ Constantine 1, Fac Sci Exactes, Lab Prod Nat Origine Vegetale & Synthese Organ, Constantine 25000, Algeria

[2] Univ Constantine 1, Unite Rech Chim Environm & Mol Struct, Constantine 25000, Algeria

[3] Univ Rennes 1, CNRS, Ctr Diffractometrie 10, UMR 6226, F-35042 Rennes, France

来源：

LETTERS IN ORGANIC CHEMISTRY | 2014年 / 11卷 / 03期

关键词：

Transposition reaction; 4-nitroimidazole; 5-nitroimidazole; crystal structure; NITROIMIDAZOLE DERIVATIVES; SUBSTITUTION; REDUCTION;

D O I：

10.2174/15701786113106660090

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This study describes the synthesis of novel 4-nitro-2-substitutedimidazole derivatives via a transposition reaction of nitro group. Conversion of 5-nitro-2-phenylethanol (styryl) imidazole derivatives into the corresponding 4-nitroisomers was achieved in good yields in nitrobenzene using a catalytic amount of methyl iodide. Spectroscopic study and single crystal X-ray structures are reported for five compounds to understand the conformational structures of these compounds.

引用

页码：174 / 179

页数：6

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