Palladium-catalyzed homocoupling reactions between two Csp3-Csp3 centers

被引：43

作者：

Lei, AW ^{[1
]}

Zhang, XM ^{[1
]}

机构：

[1] Penn State Univ, Davey Lab 152, Dept Chem, University Pk, PA 16802 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 14期

关键词：

D O I：

10.1021/ol0258536

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A novel palladium-catalyzed coupling reaction between two Csp(3)-Csp(3) centers has been investigated. This protocol is initiated by the oxidative addition of an alpha-halo carbonyl compound to a palladium(0) species, followed by the double transmetalation. The key dialkyl palladium intermediate undergoes reductive elimination to form the desired coupling product.

引用

页码：2285 / 2288

页数：4

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