Successful Treatment of Aortic Endocarditis by Achromobacter xylosoxidans with Cefiderocol Combination Therapy in a Non-Hodgkin Lymphoma Patient: Case Report and Literature Review

被引：10

作者：

La Bella, Gianfranco ^{[1
,2
]}

Salvato, Francesco ^{[1
]}

Minafra, Graziano Antonio ^{[3
]}

Bottalico, Irene Francesca ^{[3
]}

Rollo, Tiziana ^{[3
]}

Barbera, Lucia ^{[3
]}

De Tullio, Samantha ^{[3
]}

Corso, Gaetano ^{[1
,3
]}

Lo Caputo, Sergio ^{[3
,4
]}

De Nittis, Rosella ^{[3
]}

Arena, Fabio ^{[1
,3
]}

机构：

[1] Univ Foggia, Dept Clin & Expt Med, I-71122 Foggia, Italy

[2] Ist Zooprofilatt Sperimentale Puglia & Basilicata, I-71121 Foggia, Italy

[3] AOU Policlin Riuniti, I-71121 Foggia, Italy

[4] Univ Foggia, Dept Med & Surg Sci, I-71121 Foggia, Italy

来源：

ANTIBIOTICS-BASEL | 2022年 / 11卷 / 12期

关键词：

bloodstream infections; Gram-negative; multi-drug resistance; siderophore; cephalosporins; PROSTHETIC VALVE ENDOCARDITIS; INFECTIVE ENDOCARDITIS;

D O I：

10.3390/antibiotics11121686

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Achromobacter xylosoxidans is a Gram-negative aerobic opportunistic bacterium, belonging to the order of Burkholderiales, that can cause infections of virtually all body districts in patients with underlying diseases. However, A. xylosoxidans has rarely been associated with infective endocarditis. The treatment of A. xylosoxidans infections is complicated by both intrinsic and acquired resistance. Here we report on a case of aortic endocarditis by A. xylosoxidans in a Non-Hodgkin lymphoma patient treated with a combination of cefiderocol and other antibiotics, and summarize the available literature.

引用

页数：8

共 32 条

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