A new antibacterial dibenzofuran-type phloroglucinol from myrtus communis linn

被引：12
作者：
Khan, Noureen [1 ]
Rasool, Shagufta [2 ]
Ali Khan, Shahid [3 ,4 ,5 ]
Bahadar Khan, Sher [4 ,5 ]
机构：
[1] Sardar Bahadur Khan Womens Univ, Dept Chem, Quetta, Pakistan
[2] Sarhad Univ Sci & Informat Technol, Dept Chem, Peshawar, Pakistan
[3] Univ Swabi, Dept Chem, Anbar 23561, Khyber Pakhtunk, Pakistan
[4] King Abdulaziz Univ, Ctr Excellence Adv Mat Res, POB 80203, Jeddah 21589, Saudi Arabia
[5] King Abdulaziz Univ, Dept Chem, POB 80203, Jeddah 21589, Saudi Arabia
来源：
NATURAL PRODUCT RESEARCH | 2020年 / 34卷 / 22期
关键词：
Phytochemical investigation; Myrtus communis Linn; phloroglucinol; spectroscopic studies; antibacterial activity; ESSENTIAL OIL; L; ANTIOXIDANT; ACYLPHLOROGLUCINOLS; LEAVES;
D O I：
10.1080/14786419.2018.1556657
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Our continuation on the bio-assay guided isolation from Myrtus communis Linn. led to the discovery of a new dibezofuran type phloroglucinol 1,1'-(1,3,7,9-tetrahydroxydibenzo[b,d]furan-2,8-diyl)bis(ethan-1-one) 1. The structure was established through detailed spectroscopic studies including one and two dimensional NMR spectroscopy and electrospray ionization high resolution mass spectrometer (ESI-HRMS). The crude acetone extract from M. communis (AMA), dichloromethane fraction (DCM), and the isolated pure compound 1 were tested against pathogenic bacteria. Compound 1 displayed higher antibacterial activity against the Gram-positive and Gram-negative Staphlocococus aureus and Escherichia coli respectively as compared to the crude extract and fractions.
引用
收藏
页码：3199 / 3204
页数：6
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