Localized amyloid in the menisci of the knee joint

被引:5
作者
Rumpelt, HJ
Braun, A
Spier, R
Suren, EG
Thies, E
机构
[1] ORTHOPAD KRANKENANSTALT,VULPIUS KLIN,BAD RAPPENAU,GERMANY
[2] KREISKRANKENHAUS MOSBACH,MOSBACH,GERMANY
[3] STADT KRANKENHAUS,CHIRURG KLIN 1,HEILBRONN,GERMANY
[4] KREISKRANKENHAUS PLATTENWALD,BAD FRIEDRICHSHALL,GERMANY
关键词
amyloid; knee joint; menisci; amyloid typing; senile amyloid;
D O I
10.1016/S0344-0338(96)80104-X
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
This is, to the best of our knowledge, the first report on amyloid deposits in menisci. Fragments of menisci gained by arthroscopy from 316 patients between 20 and 80 years of age were examined. Amyloid was found in 70% of the cases from male, as well as female patients. The amyloid amount found was always very small, but the deposits seemed to increase with age. Patients more than 50 years of age all had menisceal amyloid. Two types of deposits were observed: a) stroma - deposits in the deep central portions of the menisci (tiny dots of Intensely stained amyloid and/or ill defined patches of low staining intensity) and b) surface associated deposits: band-like amyloid imbibition of the collagenous stroma immediately beneath the surface of the menisci but not deeper than 0,2 mm. In all cases, amyloid was resistant when pretreated by KMn04 and immunohistologically antisera against amyloid types AA, AB and AF weve negative. 3/25 cases showed a reaction with an amyloid-lambda- antibody. We assume, that amyloid in menisci is a further type of localized senile amyloidosis.
引用
收藏
页码:547 / 551
页数:5
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