Particle engineering of poorly water soluble drugs by controlled precipitation

被引：0
|
作者：
Elder, EJ [1 ]
Hitt, JE
Rogers, TL
Tucker, CJ
Saghir, S
Kupperblatt, GB
Svenson, S
Evans, JC
机构：
[1] Dow Chem Co USA, Dowpharm, Midland, MI 48674 USA
[2] Dow Chem Co USA, Chem Sci, Midland, MI 48674 USA
[3] Dow Chem Co USA, Toxicol & Environm Res & Consulting, Midland, MI 48674 USA
来源：
POLYMERIC DRUG DELIVERY II: POLYMERIC MATRICES AND DRUG PARTICLE ENGINEERING | 2006年 / 924卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Controlled precipitation is a particle engineering technology under development for enhancing the aqueous dissolution rate and bioavailability of poorly water soluble drugs. Experiments with danazol and other model drugs showed that in vitro solubilization rate and in vivo absorption of the drug were improved by this technology.
引用
收藏
页码：292 / 304
页数：13
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