Prevalence and recognition of chronic kidney disease in Stockholm healthcare

被引:109
|
作者
Gasparini, Alessandro [1 ]
Evans, Marie [1 ]
Coresh, Josef [2 ]
Grams, Morgan E. [2 ,3 ]
Norin, Olof [4 ]
Qureshi, Abdul R. [1 ]
Runesson, Bjorn [1 ]
Barany, Peter [1 ]
Arnlov, Johan [5 ,6 ]
Jernberg, Tomas [7 ,8 ]
Wettermark, Bjorn [9 ,10 ]
Elinder, Carl G. [1 ,9 ]
Carrero, Juan-Jesus [1 ,11 ]
机构
[1] Karolinska Inst, Dept Clin Sci Technol & Intervent, Div Renal Med & Baxter Novum, Stockholm, Sweden
[2] Johns Hopkins Univ, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD USA
[3] Johns Hopkins Univ, Dept Med, Div Nephrol, Baltimore, MD USA
[4] Karolinska Inst, Dept Learning Informat Management & Eth, Med Management Ctr, Stockholm, Sweden
[5] Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden
[6] Univ Uppsala Hosp, Dept Med Sci, Uppsala, Sweden
[7] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
[8] Karolinska Univ Hosp, Dept Cardiol, Stockholm, Sweden
[9] Stockholm Cty Council, Publ Healthcare Serv Comm, Stockholm, Sweden
[10] Karolinska Inst, Dept Med, Ctr Pharmacoepidemiol, Stockholm, Sweden
[11] Karolinska Inst, Ctr Mol Med, Stockholm, Sweden
基金
瑞典研究理事会;
关键词
chronic renal failure; creatinine; nephrology; public health; referral; GLOMERULAR-FILTRATION-RATE; RISK; CKD; FAILURE; MANAGEMENT; DATABASES; EQUATION; OUTCOMES; BURDEN; IMPACT;
D O I
10.1093/ndt/gfw354
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Background. Chronic kidney disease (CKD) is common, but the frequency of albuminuria testing and referral to nephrology care has been difficult to measure. We here characterize CKD prevalence and recognition in a complete healthcare utilization cohort of the Stockholm region, in Sweden. Methods. We included all adult individuals (n = 1 128 058) with at least one outpatient measurement of IDMS-calibrated serum creatinine during 2006-11. Estimated glomerular filtration rate (eGFR) was calculated via the CKD-EPI equation and CKD was solely defined as eGFR <60 mL/min/1.73 m(2). We also assessed the performance of diagnostic testing (albuminuria), nephrology consultations, and utilization of ICD-10 diagnoses. Results. A total of 68 894 individuals had CKD, with a crude CKD prevalence of 6.11% [95% confidence interval (CI): 6.07-6.16%] and a prevalence standardized to the European population of 5.38% (5.33-5.42%). CKD was more prevalent among the elderly (28% prevalence >75 years old), women (6.85 versus 5.24% in men), and individuals with diabetes (17%), hypertension (17%) or cardiovascular disease (31%). The frequency of albuminuria monitoring was low, with 38% of diabetics and 27% of CKD individuals undergoing albuminuria testing over 2 years. Twenty-three per cent of the 16 383 individuals satisfying selected KDIGO criteria for nephrology referral visited a nephrologist. Twelve per cent of CKD patients carried an ICD-10 diagnostic code of CKD. Conclusions. An estimated 6% of the adult Stockholm population accessing healthcare has CKD, but the frequency of albuminuria testing, nephrology consultations and registration of CKD diagnoses was suboptimal despite universal care. Improving provider awareness and treatment of CKD could have a significant public health impact.
引用
收藏
页码:2086 / 2094
页数:9
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