Platypnoea-orthodeoxia syndrome, an underdiagnosed cause of hypoxaemia: four cases and the possible underlying mechanisms

被引：8

作者：

Nassif, M. ^{[1
]}

Lu, H. ^{[1
]}

Konings, T. C. ^{[2
]}

Bouma, B. J. ^{[1
]}

Noordegraaf, A. Vonk ^{[3
]}

Straver, B. ^{[1
,4
]}

Blom, N. A. ^{[1
,4
,5
]}

Clur, S. A. ^{[4
]}

Backx, A. P. C. M. ^{[1
,4
]}

Groenink, M. ^{[1
]}

Boekholdt, S. M. ^{[1
]}

Koolbergen, D. R. ^{[6
,7
]}

Hazekamp, M. G. ^{[6
,7
]}

Mulder, B. J. M. ^{[1
,8
]}

de Winter, R. J. ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Cardiac Catheterizat Lab, Dept Cardiol, NL-1100 DD Amsterdam, Netherlands

[2] Vrije Univ Amsterdam Med Ctr, Dept Cardiol, Amsterdam, Netherlands

[3] Vrije Univ Amsterdam Med Ctr, Dept Pulm Med, Amsterdam, Netherlands

[4] Univ Amsterdam, Acad Med Ctr, Dept Pediat Cardiol, NL-1100 DD Amsterdam, Netherlands

[5] Leiden Univ, Med Ctr, Dept Pediat Cardiol, Leiden, Netherlands

[6] Univ Amsterdam, Acad Med Ctr, Dept Cardiothorac Surg, NL-1100 DD Amsterdam, Netherlands

[7] Leiden Univ, Med Ctr, Dept Pediat Cardiac Surg, Leiden, Netherlands

[8] Interuniv Cardiol Inst Netherlands, Utrecht, Netherlands

来源：

NETHERLANDS HEART JOURNAL | 2015年 / 23卷 / 11期

关键词：

Platypnoea-orthodeoxia; Dyspnoea; Foramen ovale; patent; Atrial septum; Mechanism; PATENT FORAMEN OVALE; PNEUMONECTOMY;

D O I：

10.1007/s12471-015-0714-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cardiac platypnoea-orthodeoxia syndrome (POS) is a position-dependent condition of dyspnoea and hypoxaemia due to right-to-left shunting. It often remains unrecognised in clinical practice, possibly because of its complex underlying pathophysiology. We present four consecutive patients with POS and patent foramen ovale (PFO) who underwent a successful percutaneous PFO closure, describe the mechanism of their POS and provide a review of the literature.

引用

页码：539 / 545

页数：7

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