Lipid based biocompatible ionic liquids: synthesis, characterization and biocompatibility evaluation

被引：24
作者：
Uddin, Shihab [1 ]
Chowdhury, Md. Raihan [1 ]
Wakabayashi, Rie [1 ]
Kamiya, Noriho [1 ,2 ,3 ]
Moniruzzaman, Muhammad [4 ]
Goto, Masahiro [1 ,2 ,3 ]
机构：
[1] Kyushu Univ, Dept Appl Chem, Grad Sch Engn, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan
[2] Kyushu Univ, Adv Transdermal Drug Delivery Syst Ctr, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan
[3] Kyushu Univ, Div Biotechnol, Ctr Future Chem, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan
[4] Univ Teknol Petronas, Chem Engn Dept, Seri Iskandar 32610, Perak, Malaysia
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 89期
关键词：
DELIVERY;
D O I：
10.1039/d0cc04491a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report a new series of lipid-based biocompatible ionic liquids (LBILs) consisting of the long-chain phosphonium compound 1,2-dimyristoyl-sn-glycero-3-ethyl-phosphatidylcholine as the cation and the long-chain fatty acids stearic acid, oleic acid, or linoleic acid as anions. Thesematerials were found to be completely miscible with many polar and nonpolar organic solvents as well as dispersible in water. These LBILs also exhibited excellent biocompatibility with an artificial three-dimensional human epidermis model.
引用
收藏
页码：13756 / 13759
页数：4
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