Meatal Intraurethral Warts Successfully Treated with 5-fluorouracil Cream

Condyloma acuminatum relatively rarely involves the urethra, and when it does it is usually only in the most distal por-tion of the urethra. A number of treatments have been described for urethral condylomas. These treatments are extensive and vari-able, comprising laser treatment, electrosurgery, cryotherapy, and topical application of cytotoxic agents such as 80% trichloroacetic acid, 5-fluorouracil cream (5-FU), podophyllin, podophyllotoxin, and imiquimod. Laser is still considered to be therapy of choice for treat-ment of intrauretral condylomata. We present the case of a 25-year-old male patient with meatal intraurethral warts who was success-fully treated with 5-FU, after many unsuccessful treatment attempts with laser treatment, electrosurgery, cryotherapy, imiquimod, and 80% trichloroacetic acid.