One-pot three-component condensation for the synthesis of 2,4,6-triarylpyridines and evaluation of their antimicrobial activity

被引：5

作者：

Ashok, D. ^{[1
]}

Reddy, M. Ram ^{[1
]}

Dharavath, Ravinder ^{[1
]}

Nagaraju, Nalaparaju ^{[1
]}

Ramakrishna, Katta ^{[1
]}

Gundu, Srinivas ^{[1
]}

Sarasija, M. ^{[2
]}

机构：

[1] Osmania Univ, Green & Med Chem Lab, Dept Chem, Hyderabad 500007, Telangana, India

[2] Satavahana Univ, Dept Chem, Karimnagar 505001, Telangana, India

来源：

JOURNAL OF CHEMICAL SCIENCES | 2021年 / 133卷 / 01期

关键词：

2,4,6-triarylpyridine; aldehyde; ammonium acetate; sealed-tube; antimicrobial;

D O I：

10.1007/s12039-021-01883-9

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new series of 2,4,6-triarylpyridines are synthesised through one-pot three-component condensation of triazole pyrazolyl aldehydes and acetophenones with ammonium acetate in moderate to good yields. The structures of the synthesised compounds are confirmed by spectral methods viz. IR, H-1 NMR, C-13 NMR and mass spectral analysis. All these scaffolds are evaluated for their in vitro antimicrobial activity and found to exhibit promising antimicrobial potency.

引用

页数：8

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