Feasibility of Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Essential Tremor in the Setting of Prior Craniotomy

被引:6
|
作者
Wathen, Connor [1 ]
Yang, Andrew, I [1 ]
Hitti, Frederick L. [1 ]
Henry, Lenora [2 ]
Chaibainou, Hanane [1 ]
Baltuch, Gordon H. [1 ]
机构
[1] Univ Penn, Perelman Sch Med, Dept Neurosurg, 8W Spruce St, Philadelphia, PA 19106 USA
[2] InSightec Inc, Miami, FL USA
关键词
Magnetic resonance-guided focused ultrasound; MRgFUS; Thalamotomy; Essential tremor; ET; SAFETY;
D O I
10.1227/ONS.0000000000000012
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BACKGROUND:Magnetic resonance imaging-guided focused ultrasound (MRgFUS) thalamotomy is a rapidly evolving therapy for the treatment of essential tremor. Although the skull is a major determinant of the delivery of acoustic energy to the target, how the presence of a prior craniotomy must be accounted for during lesioning is unclear. OBJECTIVE:To demonstrate novel application of this therapeutic option in a patient with a history of prior craniotomies for unrelated intracranial pathologies. METHODS:A 55-yr-old man with a history of right frontal craniotomy for resection of a colloid cyst underwent a left ventrointermedius nucleus thalamotomy through MRgFUS. The prior craniotomy flap was not excluded in the treatment plan; however, all bony defects and hardware were marked as "no-pass" regions. Clinical outcomes were collected at the 6-mo follow-up. RESULTS:Transducer elements whose acoustic paths would have been altered by the craniotomy defect were turned off. Sonications reaching lesional temperatures of up to 56 degrees C were successfully delivered. The procedure was well-tolerated, without any persistent intra-ablation or postablation adverse effects. The presence of a lesion was confirmed on MRI, which was associated with a significant reduction in the patient's tremor that was sustained at the 6-mo follow-up. CONCLUSION:This case demonstrates the safety and efficacy of MRgFUS thalamotomy in a patient with prior craniotomies and highlights our strategy for acoustic lesioning in this setting.
引用
收藏
页码:61 / 65
页数:5
相关论文
共 50 条
  • [31] Magnetic resonance-guided focused ultrasound for the treatment of tremor
    Yamamoto, Kazuaki
    Sarica, Can
    Loh, Aaron
    Vetkas, Artur
    Samuel, Nardin
    Milano, Vanessa
    Zemmar, Ajmal
    Germann, Juergen
    Cheyuo, Cletus
    Boutet, Alexandre
    Elias, Gavin J. B.
    Ito, Hisashi
    Taira, Takaomi
    Lozano, Andres M.
    EXPERT REVIEW OF NEUROTHERAPEUTICS, 2022, 22 (10) : 849 - 861
  • [32] Comparative Evaluation of Magnetic Resonance-Guided Focused Ultrasound Surgery for Essential Tremor
    Kim, Minsoo
    Jung, Na Young
    Park, Chang Kyu
    Chang, Won Seok
    Jung, Hyun Ho
    Chang, Jin Woo
    STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 2017, 95 (04) : 279 - 286
  • [33] Magnetic Resonance Guided Focused Ultrasound for Unilateral Thalamotomy in Medication Refractory Essential Tremor
    Lipsman, Nir
    Schwartz, Michael
    Huang, Yuexi
    Hynynen, Kullervo
    Sankar, Tejas
    Lozano, Andres M.
    STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 2013, 91 : 10 - 10
  • [34] Bilateral Magnetic Resonance Imaging-Guided Focused Ultrasound Thalamotomy for Essential Tremor
    Fukutome, Kenji
    Hirabayashi, Hidehiro
    Osakada, Yosuke
    Kuga, Yoshihiro
    Ohnishi, Hideyuki
    STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 2022, 100 (01) : 44 - 52
  • [35] Feasibility of Magnetic Resonance-Compatible Accelerometers to Monitor Tremor Fluctuations During Magnetic Resonance-Guided Focused Ultrasound Thalamotomy: Technical Note
    Baek, Hongchae
    Chen, Jacqueline
    Lockwood, Daniel
    Obusez, Emmanuel
    Poturalski, Matthew
    Nagel, Sean J.
    Jones, Stephen E.
    OPERATIVE NEUROSURGERY, 2023, 24 (06) : 641 - 650
  • [36] Safety and Efficacy of Bilateral Magnetic Resonance-Guided Focused Ultrasounds (FUS) Thalamotomy for Refractory Essential Tremor
    Vilas, D.
    Ispierto, L.
    Tardaguila, M.
    Munoz, J.
    Gonzalez, A.
    Perez, J. A.
    Garcia, R.
    Alvarez, R.
    MOVEMENT DISORDERS, 2024, 39 : S512 - S512
  • [37] Skull Density Ratio and Treatment Outcomes in Essential Tremor Patients Treated With Transcranial Magnetic Resonance-Guided Focused Ultrasound Thalamotomy
    Ahmed, Abdul-Kareem
    Zhuo, Jiachen
    Eisenberg, Howard M.
    Miller, Timothy R.
    Gullapalli, Rao
    Gandhi, Dheeraj
    NEUROSURGERY, 2019, 66 : 155 - 155
  • [38] Cognitive outcomes following unilateral magnetic resonance-guided focused ultrasound thalamotomy for essential tremor: findings from two cohorts
    Petersen, Julie
    Mcgough, Josh
    Gopinath, Georgia
    Scantlebury, Nadia
    Tripathi, Richa
    Brandmeir, Cheryl
    Boshmaf, Silina Z.
    Brandmeir, Nicholas J.
    Sewell, Isabella J.
    Konrad, Peter E.
    Abrahao, Agessandro
    Murray, Ann
    Lam, Benjamin
    Ranjan, Manish
    Hamani, Clement
    Frey, Jessica
    Rohringer, Camryn
    Mcsweeney, Melissa
    Mahoney, James J.
    Schwartz, Michael L.
    Rezai, Ali
    Lipsman, Nir
    Scarisbrick, David M.
    Rabin, Jennifer S.
    BRAIN COMMUNICATIONS, 2024, 6 (05)
  • [39] Volumetric analysis of magnetic resonance-guided focused ultrasound thalamotomy lesions
    Harary, Maya
    Essayed, Walid I.
    Valdes, Pablo A.
    McDannold, Nathan
    Cosgrove, G. Rees
    NEUROSURGICAL FOCUS, 2018, 44 (02)
  • [40] Unilateral magnetic resonance guided focused ultrasound thalamotomy for essential tremor: practices and clinicoradiological outcomes
    Chang, Won Seok
    Jung, Hyun Ho
    Kweon, Eun Jung
    Zadicario, Eyal
    Rachmilevitch, Itay
    Chang, Jin Woo
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2015, 86 (03): : 257 - 264