Carbon nanotube-based transducers for immunoassays

被引：34
|
作者：
Lynam, Carol [1 ,2 ,3 ]
Gilmartin, Niamh [1 ,2 ]
Minett, Andrew I. [3 ]
O'Kennedy, Richard [1 ,2 ]
Wallace, Gordon [3 ]
机构：
[1] Dublin City Univ, Natl Ctr Sensor Res, Biomed Diagnost Inst, Dublin 9, Ireland
[2] Dublin City Univ, Natl Ctr Sensor Res, Sch Biotechnol, Dublin 9, Ireland
[3] Univ Wollongong, Intelligent Polymer Res Inst, ARC Ctr Excellence Electromat Sci, Wollongong, NSW 2522, Australia
来源：
CARBON | 2009年 / 47卷 / 10期
基金：
爱尔兰科学基金会; 澳大利亚研究理事会;
关键词：
DIRECT ELECTROCHEMISTRY; BIOSENSORS; ELECTRODE; BEHAVIOR; FUNCTIONALIZATION; IMMOBILIZATION;
D O I：
10.1016/j.carbon.2009.04.017
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The attachment of mouse immunoglobulin G (IgG) and anti-mouse IgG antibodies onto carbon nanotubes (CNTs), using either non-covalent or covalent means was investigated. The resultant CNTs were characterised using a variety of techniques including enzyme-linked and fluorescence-linked immunoassays, UV-visible-NIR and Raman spectroscopy, transmission electron microscopy and cyclic voltammetry. TEM images of the adsorbed antibody on the CNTs show that the covalent modification approach was successful, whereas the non-covalent approach resulted in no electrochemically detectable labelled antibody. Direct electrical communication between CNTs covalently linked to peroxidase-labelled antibodies was observed during cyclic voltammetry, which suggests applications in developing carbon-nanotube-based immunosensors. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2337 / 2343
页数：7
相关论文
共 50 条
  • [1] Carbon Nanotube-Based Chemiresistive Sensors
    Tang, Ruixian
    Shi, Yongji
    Hou, Zhongyu
    Wei, Liangming
    SENSORS, 2017, 17 (04)
  • [2] Carbon nanotube-based DNA biosensor for monitoring phenolic pollutants
    Zheng, Yanqiong
    Yang, Changzhu
    Pu, Wenhong
    Zhang, Jingdong
    MICROCHIMICA ACTA, 2009, 166 (1-2) : 21 - 26
  • [3] Computational modeling of a carbon nanotube-based DNA nanosensor
    Kalantari-Nejad, R.
    Bahrami, M.
    Rafii-Tabar, H.
    Rungger, I.
    Sanvito, S.
    NANOTECHNOLOGY, 2010, 21 (44)
  • [4] Carbon Nanotube-Based Polymer Composite Thermoelectric Generators
    Hewitt, Corey A.
    Carroll, David L.
    POLYMER COMPOSITES FOR ENERGY HARVESTING, CONVERSION, AND STORAGE, 2014, 1161 : 191 - 211
  • [5] Wearable Carbon Nanotube-Based Biosensors on Gloves for Lactate
    Luo, Xiaojin
    Shi, Weihua
    Yu, Haoming
    Xie, Zhaoyang
    Li, Kunyi
    Cui, Yue
    SENSORS, 2018, 18 (10)
  • [6] The Crystallization of Polypropylene in Multiwall Carbon Nanotube-Based Composites
    Marco, Carlos
    Naffakh, Mohammed
    Gomez, Marian A.
    Santoro, Gonzalo
    Ellis, Gary
    POLYMER COMPOSITES, 2011, 32 (02) : 324 - 333
  • [7] Carbon nanotube-based flexible biocathode for enzymatic biofuel cells by spray coating
    Ben Tahar, Awatef
    Romdhane, Ahlem
    Lalaoui, Noemie
    Reverdy-Bruas, Nadege
    Le Goff, Alan
    Holzinger, Michael
    Cosnier, Serge
    Chaussy, Didier
    Belgacem, Naceur
    JOURNAL OF POWER SOURCES, 2018, 408 : 1 - 6
  • [8] Application of Raman spectroscopy in carbon nanotube-based polymer composites
    Gao Yun
    Li LingYun
    Tan PingHeng
    Liu LuQi
    Zhang Zhong
    CHINESE SCIENCE BULLETIN, 2010, 55 (35): : 3978 - 3988
  • [9] Carbon Nanotube-Based Piezoresistive Sensors Fabricated by Microwave Irradiation
    Herren, Blake
    Saha, Mrinal C.
    Liu, Yingtao
    ADVANCED ENGINEERING MATERIALS, 2020, 22 (02)
  • [10] Recent advances in carbon nanotube-based biosensors for biomolecular detection
    Dai, Benhui
    Zhou, Ruiyun
    Ping, Jianfeng
    Ying, Yibin
    Xie, Lijuan
    TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2022, 154
12345