Electrochemical synthesis of benzoxazoles from anilides - a new approach to employ amidyl radical intermediates

被引：82

作者：

Gieshoff, Tile ^{[1
,2
]}

Kehl, Anton ^{[1
]}

Schollmeyer, Dieter ^{[1
]}

Moeller, Kevin D. ^{[3
]}

Waldvogel, Siegfried R. ^{[1
,2
]}

机构：

[1] Johannes Gutenberg Univ Mainz, Inst Organ Chem, Duesbergweg 10-14, D-55128 Mainz, Germany

[2] Grad Sch Mat Sci Mainz, Staudingerweg 9, D-55128 Mainz, Germany

[3] Washington Univ, Dept Chem, St Louis, MO 63130 USA

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 20期

基金：

美国国家科学基金会;

关键词：

CROSS-COUPLING REACTION; H AMINATION SYNTHESIS; CYCLIZATION REACTIONS; BOND FORMATION; ELECTROORGANIC SYNTHESIS; ELECTRON-TRANSFER; C-N; FUNCTIONALIZATION; DERIVATIVES; GENERATION;

D O I：

10.1039/c7cc00927e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel electrochemical method for the synthesis of benzoxazoles from readily available anilides is reported. Various functionalities are tolerated and good yields can be achieved. By employing common electrode materials and a simple constant current protocol, this method is an attractive new alternative to conventional pathways.

引用

页码：2974 / 2977

页数：4

共 79 条

[1] Organocatalytic Syntheses of Benzoxazoles and Benzothiazoles using Aryl Iodide and Oxone via C-H Functionalization and C-O/S Bond Formation [J].