COVID-19 and venous thromboembolism: A narrative review

被引：20

作者：

Angelini, Dana E. ^{[1
]}

Kaatz, Scott ^{[2
]}

Rosovsky, Rachel P. ^{[3
]}

Zon, Rebecca L. ^{[4
,5
]}

Pillai, Shreejith ^{[2
]}

Robertson, William E. ^{[6
]}

Elavalakanar, Pavania ^{[7
]}

Patell, Rushad ^{[7
]}

Khorana, Alok ^{[1
]}

机构：

[1] Cleveland Clin Fdn, Taussig Canc Inst, Dept Hematol & Med Oncol, 9500 Euclid Ave, Cleveland, OH 44195 USA

[2] Henry Ford Hosp, Div Hosp Med, Detroit, MI USA

[3] Massachusetts Gen Hosp, Dept Med, Boston, MA USA

[4] Dana Farber Canc Inst, Boston, MA USA

[5] Massachusetts Gen Brigham, Boston, MA USA

[6] Weber State Univ, Dept Emergency Healthcare, Dumke Coll Hlth Profess, Natl Blood Clot Alliance, Ogden, UT USA

[7] Beth Israel Deaconess Med Ctr, Div Hematol & Hematol Malignancies, Boston, MA USA

来源：

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS | 2022年 / 6卷 / 02期

关键词：

COVID-19; incidence; review; therapeutics; venous thromboembolism; THROMBOSIS; MORTALITY; VTE;

D O I：

10.1002/rth2.12666

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) is associated with coagulopathy through numerous mechanisms. The reported incidence of venous thromboembolism (VTE) in hospitalized patients with COVID-19 has varied widely, and several meta-analyses have been performed to assess the overall prevalence of VTE. The novelty of this coronavirus strain along with its unique mechanisms for microvascular and macrovascular thrombosis has led to uncertainty as to how to diagnose, prevent, and treat thrombosis in patients affected by this virus. This review discusses the epidemiology and pathophysiology of thrombosis in the setting of SARS-CoV-2 infection along with an updated review on the preventative and treatment strategies for VTE associated with SARS-CoV-2 infection.

引用

页数：15

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