Cartilage Tissue Engineering Using Combination of Chitosan Hydrogel and Mesenchymal Stem Cells

被引：3

作者：

Yuan, Dechao ^{[1
,2
,3
]}

Chen, Zhu ^{[1
,2
]}

Lin, Tao ^{[1
,2
]}

Luo, Xuwei ^{[1
,2
]}

Dong, Hua ^{[4
]}

Feng, Gang ^{[1
,2
,3
]}

机构：

[1] Nanchong Cent Hosp, Inst Tissue Engn & Stem Cells, Nanchong 637000, Sichuan, Peoples R China

[2] North Sichuan Med Univ, Clin Inst 2, Nanchong 637000, Sichuan, Peoples R China

[3] Sichuan Med Univ, Luzhou 646000, Sichuan, Peoples R China

[4] Univ Edinburgh, Sch Chem, Edinburgh EH9 3JF, Midlothian, Scotland

来源：

JOURNAL OF CHEMISTRY | 2015年 / 2015卷

关键词：

REPAIR; DIFFERENTIATION; LESIONS; STRATEGIES; DEFECTS; GROWTH;

D O I：

10.1155/2015/530607

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel chitosan hydrogel with high porosity was fabricated by a crosslinking method. Cartilage tissue engineering formed after mesenchymal stem cells was cultured on this hydrogel scaffold for 12 weeks. The immunohistochemistry tests demonstrated that the obtained cartilage had the specific histological properties of natural cartilage. And the qPCR tests also proved that the genes for type II collagen in the obtained cartilage were expressed the same as in the natural one.

引用

页数：6

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