Fluorescent chemosensors for carbohydrates: A decade's worth of bright spies for saccharides in review

被引:150
作者
Cao, HS [1 ]
Heagy, MD [1 ]
机构
[1] New Mexico Inst Min & Technol, Socorro, NM 87801 USA
关键词
fluorescent probes; saccharides; boronic acids; ICT; PET; FRET;
D O I
10.1023/B:JOFL.0000039344.34642.4c
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This review provides a chronological survey of over fifty fluorescent chemosensors for carbohydrates from the period between 1992 to the present. The survey contains only those sensors that are synthetic or chemosensory, utilize boronic acids and display a fluorescence response in the form of intensity changes or shifts in wavelength. With each compound listed, a description of the saccharide probe is given with regard to concentration, excitation and emission wavelengths, pH and solvent mixture proportions. In addition, the selectivity of each chemosensor is provided as well as the trends in binding constants. Where possible, a description of the fluorescence signaling mechanism is given as well as commentary on the probe's unique features within this class of sensors.
引用
收藏
页码:569 / 584
页数:16
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