Integration of medicinal plants into the traditional system of medicine for the treatment of cancer in Sokoto State, Nigeria

被引：13

作者：

Malami, Ibrahim ^{[1
,2
]}

Jagaba, Nasiru Muhammad ^{[1
]}

Abubakar, Ibrahim Babangida ^{[3
]}

Muhammad, Aliyu ^{[4
]}

Alhassan, Alhassan Muhammad ^{[5
]}

Waziri, Peter Maitama ^{[6
]}

Yahaya, Ibrahim Zakiyya Yakubu ^{[1
]}

Mshelia, Halilu Emmanuel ^{[1
]}

Mathias, Sylvester Nefy ^{[1
]}

机构：

[1] Usmanu Danfodiyo Univ, Fac Pharmaceut Sci, Dept Pharmacognosy & Ethnopharm, PMB 2346, Sokoto, Nigeria

[2] Usmanu Danfodiyo Univ, Ctr Adv Med Res & Training CAMRET, PMB 2346, Sokoto, Nigeria

[3] Kebbi State Univ Sci & Technol, Dept Biochem, Fac Life Sci, PMB 1144, Aliero, Kebbi State, Nigeria

[4] Ahmadu Bello Univ Zaria, Dept Biochem, Fac Life Sci, Zaria 810271, Nigeria

[5] Usmanu Danfodiyo Univ, Dept Pharmaceut & Med Chem, Fac Pharmaceut Sci, PMB 2346, Sokoto, Nigeria

[6] Kaduna State Univ, Dept Biochem, Main Campus,PMB 2336, Kaduna, Nigeria

来源：

HELIYON | 2020年 / 6卷 / 09期

关键词：

Alternative medicine; Cancer research; Ethnopharmacology; Pharmaceutical science; Pharmacology; Traditional medicine practice; Cancer; Integrative medicine; Medicinal plants; Ethnobotanical survey; Sokoto state; TRACT UROTHELIAL CARCINOMA; IN-SITU PROLIFERATION; TAMARINDUS-INDICA L; HUMAN LEUKEMIA-CELLS; ACUTE-RENAL-FAILURE; MANGIFERA-INDICA; ACACIA-NILOTICA; ZINGIBER-OFFICINALE; ARISTOLOCHIC ACID; OCIMUM-GRATISSIMUM;

D O I：

10.1016/j.heliyon.2020.e04830

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This study was designed to explore and record various medicinal plants integrated into the traditional system of medicine for the treatment of cancer. The traditional system of medicine is a routine practiced among the indigenous ethnic groups of Sokoto state. A semi-structured questionnaire was designed and used for data collection around the selected Local Government Areas. A substantial number of plant species were identified, recorded, and collected for preservation. Data collected for each specie was analysed to assess its frequent use among the medicinal plants. A total of 67 species belonging to 31 families have been identified and recorded. Out of the 473 frequency of citation (FC), Acacia nilotica was the most frequently cited specie (32 FC, 64% FC, 0.6 RFC), followed by Guiera senegalensis (27 FC, 54% FC, 0.5 RFC), Erythrina sigmoidea (17 FC, 34% FC, 0.3 RFC), and subsequently Combretum camporum (15 FC, 30% FC, 0.3 RFC). The most common parts of the plants used include the barks (55.2%), the roots (53.2%), and the leaves (41.8%). Additionally, decoction (74.6%), powdered form (49.3%), and maceration (46.3%) are the most frequently used mode of preparation. The historical knowledge of a traditional system of medicine practiced by the native traditional healers of Sokoto for the treatment of cancer has been documented. The present study further provides a baseline for future pharmacological investigations into the beneficial effects of such medicinal plants for the treatment of cancer.

引用

页数：13

共 209 条

[61] Differential control of growth, apoptotic activity and gene expression in human colon cancer cells by extracts derived from medicinal herbs, Rhazya stricta and Zingiber officinale and their combination [J].