Role of presymptomatic transmission of COVID-19: evidence from Beijing, China

被引：15

作者：

Zhang, Yi ^{[1
,2
]}

Muscatello, David ^{[3
]}

Tian, Yi ^{[1
,2
]}

Chen, Yanwei ^{[1
,2
]}

Li, Shuang ^{[1
,2
]}

Duan, Wei ^{[1
,2
]}

Ma, Chunna ^{[1
,2
]}

Sun, Ying ^{[1
,2
]}

Wu, Shuangsheng ^{[1
,2
]}

Ge, Lin ^{[4
]}

Yang, Peng ^{[1
,2
]}

Jia, Lei ^{[1
,2
]}

Wang, Quanyi ^{[1
,2
]}

MacIntyre, Chandini Raina ^{[3
,5
]}

机构：

[1] Beijing Ctr Dis Prevent & Control, Beijing, Peoples R China

[2] Beijing Res Ctr Prevent Med, Beijing, Peoples R China

[3] Univ New South Wales, Sydney, NSW, Australia

[4] Univ Nevada Las Vegas, Las Vegas, NV USA

[5] Arizona State Univ, Tempe, AZ USA

来源：

JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH | 2021年 / 75卷 / 01期

关键词：

Communicable diseases; control of diseases; public health policy;

D O I：

10.1136/jech-2020-214635

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background The presymptomatic transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been documented in limited clusters, and it is predicted through modelling. However, there is a lack of evidence from observations with a large sample size. Methods We used data from meticulous contact tracing of people exposed to cases of SARS-CoV-2 to estimate the proportion of cases that result from the presymptomatic transmission of the virus in Beijing during January 2020 and February 2020. Results The results showed that presymptomatic transmission occurred in at least 15% of 100 secondary COVID-19 cases. The earliest presymptomatic contact event occurred 5 days prior to the index case's onset of symptoms, and this occurred in two clusters. Conclusions The finding suggested that the contact tracing period should be earlier and highlighted the importance of preventing transmission opportunities well before the onset of symptoms.

引用

页码：84 / 87

页数：4

共 8 条

[1] Presumed Asymptomatic Carrier Transmission of COVID-19 [J].

Bai, Yan ;

Yao, Lingsheng ;

Wei, Tao ;

Tian, Fei ;

Jin, Dong-Yan ;

Chen, Lijuan ;

Wang, Meiyun .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (14) :1406-1407

[2]

Du ZW, 2020, EMERG INFECT DIS, V26, P1341, DOI [10.3201/eid2606.200357, 10.1101/2020.02.19.20025452]

[3] Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility - King County, Washington, March 2020 [J].

Kimball, Anne ;

Hatfield, Kelly M. ;

Arons, Melissa ;

James, Allison ;

Taylor, Joanne ;

Spicer, Kevin ;

Bardossy, Ana C. ;

Oakley, Lisa P. ;

Tanwar, Sukarma ;

Chisty, Zeshan ;

Bell, Jeneita M. ;

Methner, Mark ;

Harney, Josh ;

Jacobs, Jesica R. ;

Carlson, Christina M. ;

McLaughlin, Heather P. ;

Stone, Nimalie ;

Clark, Shauna ;

Brostrom-Smith, Claire ;

Page, Libby C. ;

Kay, Meagan ;

Lewis, James ;

Russell, Denny ;

Hiatt, Brian ;

Gant, Jessica ;

Duchin, Jeffrey S. ;

Clark, Thomas A. ;

Honein, Margaret A. ;

Reddy, Sujan C. ;

Jernigan, John A. .

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2020, 69 (13) :377-381

[4]

Morag H, 2020, CGTN

[5]

National Health Commission of China, 2020, 5 VERS CHIN GUID GOV

[6] COVID-19 Transmission Within a Family Cluster by Presymptomatic Carriers in China [J].

Qian, Guoqing ;

Yang, Naibin ;

Ma, Ada Hoi Yan ;

Wang, Liping ;

Li, Guoxiang ;

Chen, Xueqin ;

Chen, Xiaomin .

CLINICAL INFECTIOUS DISEASES, 2020, 71 (15) :861-862

[7] Potential Presymptomatic Transmission of SARS-CoV-2, Zhejiang Province, China, 2020 [J].

Tong, Zhen-Dong ;

Tang, An ;

Li, Ke-Feng ;

Li, Peng ;

Wang, Hong-Ling ;

Yi, Jing-Ping ;

Zhang, Yong-Li ;

Yan, Jian-Bo .

EMERGING INFECTIOUS DISEASES, 2020, 26 (05) :1052-1054

[8] Presymptomatic Transmission of SARS-CoV-2-Singapore, January 23-March 16, 2020 [J].

Wei, Wycliffe E. ;

Li, Zongbin ;

Chiew, Calvin J. ;

Yong, Sarah E. ;

Toh, Matthias P. ;

Lee, Vernon J. .

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2020, 69 (14) :411-415

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