1,8-Cineole: a review of source, biological activities, and application

被引：191

作者：

Cai, Zi-Min ^{[1
,2
,3
]}

Peng, Jian-Qing ^{[1
,2
,3
]}

Chen, Yi ^{[1
,2
,3
]}

Tao, Ling ^{[1
,2
,3
]}

Zhang, Yan-Yan ^{[1
,2
,3
]}

Fu, Ling-Yun ^{[1
,2
,3
]}

Long, Qing-De ^{[1
,2
,3
]}

Shen, Xiang-Chun ^{[1
,2
,3
]}

机构：

[1] Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Sch Pharmaceut Sci, Guiyang 550014, Peoples R China

[2] Guizhou Med Univ, High Efficacy Applicat Nat Med Resources Engn Ctr, Sch Pharmaceut Sci, Guiyang 550025, Peoples R China

[3] Guizhou Med Univ, Key Lab Optimal Utilizat Nat Med Resources, Sch Pharmaceut Sci, Guiyang 550025, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2021年 / 23卷 / 10期

基金：

中国国家自然科学基金;

关键词：

1; 8-Cineole; source; biological activity; mechanism; application; MONOTERPENES ALPHA-PINENE; TERPENOID OXIDE PRESENT; ESSENTIAL OIL; CHEMICAL-COMPOSITION; OXIDATIVE STRESS; DOUBLE-BLIND; ANTIBACTERIAL ACTIVITY; MEDICINAL-PLANTS; INFLUENZA-VIRUS; EUCALYPTOL;

D O I：

10.1080/10286020.2020.1839432

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

1,8-Cineole (also known as eucalyptol) is mostly extracted from the essential oils of plants, which showed extensively pharmacological properties including anti-inflammatory and antioxidant mainly via the regulation on NF-kappa B and Nrf2, and was used for the treatment of respiratory diseases and cardiovascular, etc. Although various administration routes have been used in the application of 1.8-cineole, few formulations have been developed to improve its stability and bioavailability. This review retrospects the researches on the source, biological activities, mechanisms, and application of 1,8-cineole since 2000, which provides a view for the further studies on the application and formulations of 1,8-cineole.

引用

页码：938 / 954

页数：17

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