Ultraviolet light-mediated drug delivery: Principles, applications, and challenges

被引：139
作者：
Barhoumi, Aoune
Liu, Qian
Kohane, Daniel S. [1 ]
机构：
[1] Harvard Univ, Sch Med, Boston Childrens Hosp, Lab Biomat & Drug Delivery,Dept Anesthesiol, Boston, MA 02115 USA
来源：
JOURNAL OF CONTROLLED RELEASE | 2015年 / 219卷
关键词：
Drug delivery; UV-induced drug delivery; BLOCK-COPOLYMER MICELLES; MESOPOROUS SILICA NANOPARTICLES; NEAR-INFRARED LIGHT; STIMULI-RESPONSIVE NANOCARRIERS; UP-CONVERSION NANOPARTICLES; PHOTO-CROSS-LINKING; IN-VIVO; 2ND-HARMONIC GENERATION; UPCONVERTING NANOPARTICLES; INTRACELLULAR DELIVERY;
D O I：
10.1016/j.jconrel.2015.07.018
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
UV light has been extensively employed in drug delivery because of its versatility, ease of manipulation, and ability to induce chemical changes on the therapeutic carrier. Here we review the mechanisms by which UV light affects drug delivery systems. We will present the challenges facing UV-induced drug delivery and some of the proposed solutions. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码：31 / 42
页数：12
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