Mycobacterium tuberculosis complex and mycobacterial heat shock proteins in lymph node tissue from patients with pulmonary sarcoidosis

被引：73

作者：

Dubaniewicz, Anna

Dubaniewicz-Wybieralska, Miroslawa

Sternau, Adam

Zwolska, Zofia

Izycka-Swieszewska, Ewa

Augustynowicz-Kopec, Ewa

Skokowski, Jaroslaw

Singh, Mahavir

Zimnoch, Lech

机构：

[1] Med Univ Gdansk, Dept Pathophysiol, PL-80211 Gdansk, Poland

[2] Med Univ Gdansk, Dept Radiol, PL-80211 Gdansk, Poland

[3] Med Univ Gdansk, Dept Thorac Surg, PL-80211 Gdansk, Poland

[4] Natl Inst TB & Lung Dis, Warsaw, Poland

[5] Med Univ Gdansk, Dept Pathomorphol, PL-80211 Gdansk, Poland

[6] Med Univ Gdansk, Dept Surg Oncol, PL-80211 Gdansk, Poland

[7] LIONEX Diagnost & Therapeut GmbH, Braunschweig, Germany

[8] GBF, Braunschweig, Germany

[9] Med Univ Bialystok, Dept Med Pathomorphol, Bialystok, Poland

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2006年 / 44卷 / 09期

关键词：

D O I：

10.1128/JCM.01433-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We demonstrated that not whole Mycobacterium tuberculosis but its particular antigens, hsp70(Mtb), hsp65(Mtb), and bsp16(Mtb), are present in lymph node tissues of patients with sarcoidosis (SA). hsp16(Mtb), occurs in the early stage of SA, whereas hsp70(Mtb) occurs in stage II of SA. hsp65(Mtb) is highly expressed in the capillary vessels in lymph node tissues in patients with SA.

引用

收藏

页码：3448 / 3451

页数：4

相关论文

共 12 条

[1] Clinical evaluation of the BDProbeTec strand displacement amplification assay for rapid diagnosis of tuberculosis [J].

Bergmann, JS ;

Woods, GL .

JOURNAL OF CLINICAL MICROBIOLOGY, 1998, 36 (09) :2766-2768

[2] ATS/ERS/WASOG statement on sarcoidosis [J].

Costabel, U ;

Hunninghake, GW .

EUROPEAN RESPIRATORY JOURNAL, 1999, 14 (04) :735-737

[3] Molecular analysis of sarcoidosis tissues for Mycobacterium species DNA [J].

Drake, WP ;

Pei, ZH ;

Pride, DT ;

Collins, RD ;

Cover, TL ;

Blaser, MJ .

EMERGING INFECTIOUS DISEASES, 2002, 8 (11) :1334-1341

[4] Is there a role for microorganisms in the pathogenesis of sarcoidosis? [J].

Du Bois, RM ;

Goh, N ;

McGrath, D ;

Cullinan, P .

JOURNAL OF INTERNAL MEDICINE, 2003, 253 (01) :4-17

[5] Serum anti-mycobacteria heat shock proteins antibodies in sarcoidosis and tuberculosis [J].

Dubaniewicz, A ;

Kämpfer, S ;

Singh, M .

TUBERCULOSIS, 2006, 86 (01) :60-67

[6] Association between SLC11A1 (formerly NRAMP1) and the risk of sarcoidosis in Poland [J].

Dubaniewicz, A ;

Jamieson, SE ;

Dubaniewicz-Wybieralska, MD ;

Fakiola, M ;

Miller, EN ;

Blackwell, JM .

EUROPEAN JOURNAL OF HUMAN GENETICS, 2005, 13 (07) :829-834

[7]

Dubaniewicz A., 2004, VESTNIK MCDC, V3, P108

[8] Characterization of Mycobacterium tuberculosis complex isolates from Greek patients with sarcoidosis by spoligotyping [J].

Gazouli, M ;

Ikonomopoulos, J ;

Koundourakis, A ;

Bartos, M ;

Pavlik, I ;

Overduin, P ;

Kremer, K ;

Gorgoulis, V ;

Kittas, C .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (09) :4858-4861

[9] Immunoglobulin G, A, and M responses in serum and circulating immune complexes elicited by the 16-kilodalton antigen of Mycobacterium tuberculosis [J].

Raja, A ;

Devi, KRU ;

Ramalingam, B ;

Brennan, PJ .

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 2002, 9 (02) :308-312

[10] OCCURRENCE AND STABILITY OF INSERTION SEQUENCES IN MYCOBACTERIUM-TUBERCULOSIS COMPLEX STRAINS - EVALUATION OF AN INSERTION SEQUENCE-DEPENDENT DNA POLYMORPHISM AS A TOOL IN THE EPIDEMIOLOGY OF TUBERCULOSIS [J].

VANSOOLINGEN, D ;

HERMANS, PWM ;

DEHAAS, PEW ;

SOLL, DR ;

VANEMBDEN, JDA .

JOURNAL OF CLINICAL MICROBIOLOGY, 1991, 29 (11) :2578-2586