Direct Thioamination of Arynes via Reaction with Sulfilimines and Migratory N-Arylation

被引：118

作者：

Yoshida, Suguru ^{[1
]}

Yano, Takahisa ^{[1
]}

Misawa, Yoshihiro ^{[1
]}

Sugimura, Yasuyuki ^{[2
]}

Igawa, Kazunobu ^{[3
]}

Shimizu, Shigeomi ^{[2
]}

Tomooka, Katsuhiko ^{[3
]}

Hosoya, Takamitsu ^{[1
]}

机构：

[1] Tokyo Med & Dent Univ, Inst Biomat & Bioengn, Lab Chem Biosci, Chiyoda Ku, Tokyo 1010062, Japan

[2] Tokyo Med & Dent Univ, Med Res Inst, Dept Pathol Cell Biol, Bunkyo Ku, Tokyo 1138510, Japan

[3] Kyushu Univ, Inst Mat Chem & Engn, Kasuga, Fukuoka 8168580, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2015年 / 137卷 / 44期

关键词：

BOND FORMATION; SYNTHETIC APPLICATIONS; NUCLEOPHILIC-ADDITION; EXCHANGE-REACTION; CONCISE SYNTHESIS; CARBON-CARBON; GENERATION; INSERTION; ACTIVATION; BENZYNE;

D O I：

10.1021/jacs.5b10557

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel method for preparing a diverse range of o-sulfanylanilines is described. Direct thioamination of arynes with sulfilimines gives o-sulfanylanilines, involving C-N and C-S bond formations and migratory N-arylation.

引用

页码：14071 / 14074

页数：4

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