Single molecule force spectroscopy study of γ-polyglutamic acid by using atomic force microscopy

被引:0
作者
Ahamed, Parbhej [1 ]
Kawakami, Masaru [1 ,2 ]
Furukawa, Hidemitsu [1 ,2 ]
机构
[1] Yamagata Univ, Grad Sch Sci & Engn, Dept Mech Syst Engn, Soft & Wet Matter Engn Lab, 4-3-16 Jonan, Yonezawa, Yamagata 9928510, Japan
[2] Yamagata Univ, Life 3DPrinting Innovat Ctr LPIC, 4-3-16 Jonan, Yonezawa, Yamagata 9928510, Japan
来源
NANOSENSORS, BIOSENSORS, AND INFO-TECH SENSORS AND SYSTEMS 2016 | 2016年 / 9802卷
关键词
gamma-PGA; single molecule force spectroscopy (SMFS); atomic force microscopy (AFM);
D O I
10.1117/12.2218040
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
gamma-PGA is a versatile multi-functional biopolymer possessing much useful biological functionality. Each biological function is associated with specific properties related to various forms of gamma-PGA. However, to date, knowledge about the molecular mechanism to control specific structures of gamma-PGA under a certain environmental conditions are unknown. In this study, we used single molecule force spectroscopy (SMFS) method to characterize the structure of gamma-PGA in two environmental conditions. A water environment or 0.5 M MgCl2 salt solution was used to observe the effect of metal ion on gamma-PGA structure at room temperature. The obtained results revealed that gamma- PGA exists branched and/or cross-linked structure of gamma-PGA in water or MgCl2 salt solution.
引用
收藏
页数:5
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