Environmental Influences on Systemic Lupus Erythematosus Expression

被引：84

作者：

Kamen, Diane L. ^{[1
]}

机构：

[1] Med Univ S Carolina, Dept Med, Div Rheumatol & Immunol, Charleston, SC 29425 USA

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2014年 / 40卷 / 03期

基金：

美国国家卫生研究院;

关键词：

Systemic lupus erythematosus; Etiology; Vitamin D; Environment; Risk factors; EPSTEIN-BARR-VIRUS; VITAMIN-D DEFICIENCY; RHEUMATOID-ARTHRITIS; EPIGENETIC MECHANISMS; AUTOIMMUNE-DISEASES; MORTALITY PATTERNS; CIGARETTE-SMOKING; RISK-FACTORS; ASSOCIATION; PREVALENCE;

D O I：

10.1016/j.rdc.2014.05.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The etiology of systemic lupus erythematosus (SLE) is unknown, but multiple genetic, epigenetic, and environmental risk factors have been implicated. The inheritance of genes alone is not sufficient for developing SLE, suggesting the influence of environmental triggers on disease expression. Despite the tremendous amount of progress in elucidating potential environmental risk factors for SLE, much more needs to be done. An interdisciplinary approach to studies of the causes and, ultimately, prevention of SLE is needed. This article reviews what is understood about the relationship between environmental exposures and SLE, in addition to emerging areas of study.

引用

页码：401 / +

页数：13

共 65 条

[31]

James JA, 2001, ARTHRITIS RHEUM-US, V44, P1122, DOI 10.1002/1529-0131(200105)44:5<1122::AID-ANR193>3.3.CO

[32]

2-4

[33]

Kamen DL, 2012, ARTHRITIS RES THER, V14

[34] Autoantibody prevalence and lupus characteristics in a unique African American population [J].

Kamen, Diane L. ;

Barron, Mia ;

Parker, Tia M. ;

Shaftman, Stephanie R. ;

Bruner, Gail R. ;

Aberle, Teresa ;

James, Judith A. ;

Scofield, R. Hal ;

Harley, John B. ;

Gilkeson, Gary S. .

ARTHRITIS AND RHEUMATISM, 2008, 58 (05) :1237-1247

[35] Vitamin D and molecular actions on the immune system: modulation of innate and autoimmunity [J].

Kamen, Diane L. ;

Tangpricha, Vin .

JOURNAL OF MOLECULAR MEDICINE-JMM, 2010, 88 (05) :441-450

[36] Vitamin D deficiency in systemic lupus erythematosus [J].

Kamen, DL ;

Cooper, GS ;

Bouali, H ;

Shaftman, SR ;

Hollis, BW ;

Gilkeson, GS .

AUTOIMMUNITY REVIEWS, 2006, 5 (02) :114-117

[37] Risk modification by CYP1A1 and GSTM1 polymorphisms in the association of cigarette smoking and systemic lupus erythematosus in a Japanese population [J].

Kiyohara, C. ;

Washio, M. ;

Horiuchi, T. ;

Asami, T. ;

Ide, S. ;

Atsumi, T. ;

Kobashi, G. ;

Takahashi, H. ;

Tada, Y. .

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 2012, 41 (02) :103-109

[38]

Klack K, 2012, REV BRAS REUMATOL, V52, P384

[39]

Lertratanakul A, 2014, ARTHRITIS CARE RES H

[40] The Incidence and Prevalence of Systemic Lupus Erythematosus, 2002-2004 [J].

Lim, S. Sam ;

Bayakly, A. Rana ;

Helmick, Charles G. ;

Gordon, Caroline ;

Easley, Kirk A. ;

Drenkard, Cristina .

ARTHRITIS & RHEUMATOLOGY, 2014, 66 (02) :357-368

← 1 2 3 4 5 6 7 →