Enecarbamates as imine surrogates: Nucleophilic addition of 1,3-dicarbonyl compounds to enecarbamates

被引:48
|
作者
Kobayashi, Shu [1 ]
Gustafsson, Tomas [1 ]
Shimizu, Yusuke [1 ]
Kiyohara, Hiroshi [1 ]
Matsubara, Ryosuke [1 ]
机构
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, ERATO, Japan Sci & Technol Agcy,JSTHFRE Div,Bunkyo Ku, Tokyo 1130033, Japan
关键词
D O I
10.1021/ol0620186
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Novel Mannich-type reactions of 1,3-dicarbonyl compounds with enecarbamates have been developed. Stable and storable enecarbamates work as surrogates of aliphatic aldehyde-derived imines, which are known to be difficult to isolate and store.
引用
收藏
页码:4923 / 4925
页数:3
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