Recommendations of the French Society of Rheumatology on pharmacological treatment of knee osteoarthritis

被引:51
作者
Sellam, Jeremie [1 ]
Courties, Alice [1 ]
Eymard, Florent [2 ,3 ]
Ferrero, Stephanie
Latourte, Augustin [4 ]
Ornetti, Paul [5 ]
Bannwarth, Bernard [6 ]
Baumann, Laurence [7 ]
Berenbaum, Francis [1 ]
Chevalier, Xavier [2 ]
Ea, Hang Korng [4 ]
Fabre, Marie-Christine [8 ]
Forestier, Romain [9 ]
Grange, Laurent [10 ]
Lellouche, Henri [11 ]
Maillet, Jeremy [4 ]
Mainard, Didier [12 ]
Perrot, Serge [13 ]
Rannou, Francois [14 ]
Rat, Anne-Christine [15 ]
Roux, Christian H. [3 ]
Senbel, Eric [16 ]
Richette, Pascal [4 ]
机构
[1] Sorbonne Univ, Hop St Antoine, AP HP, Serv Rhumatol,INSERM,UMRS 938, 184 Rue Faubourg St Antoine, F-75012 Paris, France
[2] Hop Henri Mondor, AP HP, Serv Rhumatol, F-94000 Creteil, France
[3] Univ Cote Azur, CHU Nice, LAMHESS, Serv Rhumatol, F-06000 Nice, France
[4] Hop Lariboisiere, AP HP, Serv Rhumatol, F-75010 Paris, France
[5] CHU Dijon, Serv Rhumatol, F-21000 Dijon, France
[6] CHU Pellegrin, Serv Rhumatol, F-33000 Bordeaux, France
[7] Univ Paris, F-75006 Paris, France
[8] Assoc Francaise Lutte Antirhumatismale AFLAR, F-75013 Paris, France
[9] Ctr Rech Rhumatol & Thermale, F-73100 Aix Les Bains, France
[10] CHU Grenoble Alpes, AFLAR, Serv Rhumatol, F-38000 Grenoble, France
[11] Hop Lariboisiere, AP HP, Cabinet Liberal & Serv rhumatol, F-75010 Paris, France
[12] CHU Nancy, Serv Chirurg Orthoped, F-54000 Nancy, France
[13] Hop Cochin, AP HP, Ctr Devaluat & Traitement Douleur, F-75014 Paris, France
[14] Univ Paris, Hop Cochin, AP HP, Ctr Univ Paris,Serv Reeducat & Readaptat Appareil, F-75014 Paris, France
[15] CHU Caen, Serv Rhumatol, F-14000 Caen, France
[16] Hop St Marguerite, Cabinet Liberal & Serv Rhumatol, F-13000 Marseille, France
[17] UFR Med Paris Ctr, Fac Sante, F-75006 Paris, France
关键词
Knee osteoarthritis; Osteoarthritis; Treatment; Recommendations; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; STANDARDIZED OPERATING PROCEDURES; INTRAARTICULAR HYALURONIC-ACID; DOUBLE-BLIND; HIP OSTEOARTHRITIS; AMERICAN-COLLEGE; CONTROLLED-TRIAL; METAANALYSIS; EFFICACY; PAIN;
D O I
10.1016/j.jbspin.2020.09.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: To establish recommendations for pharmacological treatment of knee osteoarthritis specific to France. Methods: On behalf of the French Society of Rheumatology (SFR), a bibliography group analyzed the literature on the efficacy and safety of each pharmacological treatment for knee osteoarthritis. This group joined a multidisciplinary working group to draw up recommendations. Strength of recommendation and quality of evidence level were assigned to each recommendation. A review committee gave its level of agreement. Results: Five general principles were established: 1) need to combine pharmacological and non pharmacological treatments, 2) personalization of treatment, 3) symptomatic and/or functional aim of pharmacological treatments, 4) need to regularly re-assess the treatments and 5) discussion about arthroplasty if medical treatment fails. Six recommendations involved oral treatments: 1) paracetamol should not necessarily be prescribed systematically and/or continuously, 2) NSAIDs, possibly as first-line, 3) weak opioids, 4) strong opioids, 5) symptomatic slow-acting drugs of osteoarthritis, and 6) duloxetine (off-label use). Two recommendations involved topical agents (NSAIDs and capsaicin < 1%). Three recommendations involved intra-articular treatments: corticosteroid or hyaluronic acid injections that can be proposed to patients. The experts did not draw a conclusion about the benefits of platelet-rich plasma injections. Conclusion: These are the first recommendations of the SFR on the pharmacological treatment of knee osteoarthritis. (c) 2020 Societe francaise de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:548 / 555
页数:8
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